A Cross-Sectional Study on Knowledge, Attitude and Practice of Osteoporosis Prevention in Patients with Breast Cancer Undergoing Endocrine Therapy: A Cross-Sectional Study.

Objectives:This study aims to understand the current status of knowledge, health beliefs, and behavior related to osteoporosis prevention in patients with breast cancer during endocrine therapy and to analyze its influencing factors. Methods:From December 2022 to June 2023, convenience sampling was used to investigate patients with breast cancer receiving endocrine therapy in a Class III Grade A hospital in Shanghai using the general information questionnaire, Osteoporosis-Related preventive Behavior Questionnaire, Osteoporosis Knowledge Questionnaire (OKT), and Osteoporosis Health Belief Scale (OHBS). Results:Four hundred thirty-five questionnaires were distributed, and 403 valid questionnaires were collected, with an effective recovery rate of 92.6%. OKT failed in 282 cases (70.0%), and the standard score was (52.53 ​± ​12.01). The standard score of OHBS was (72.46 ​± ​5.79). The results of univariate analysis showed that age was negatively correlated with daily sunshine time. It was positively correlated with calcium/vitamin D supplementation and bone mineral density measurement. Multiple linear regression analysis showed that age and education level influenced OKT and OHBS scale scores (P ​< ​0.05). Pearson correlation analysis showed a significant positive correlation between OKT and OHBS (P ​< ​0.05). Conclusions:Patients with breast cancer with endocrine therapy have poor knowledge of osteoporosis and low levels of health belief, and most of them have wrong prevention behaviors.