A Deep Learning Model for Multi-Domain MRI Synthesis Using Generative Adversarial Networks

In recent years, Magnetic Resonance Imaging (MRI) has emerged as a prevalent medical imaging technique, offering comprehensive anatomical and functional information. However, the MRI data acquisition process presents several challenges, including time-consuming procedures, prone motion artifacts, and hardware constraints. To address these limitations, this study proposes a novel method that leverages the power of generative adversarial networks (GANs) to generate multi-domain MRI images from a single input MRI image. Within this framework, two primary generator architectures, namely ResUnet and StarGANs generators, were incorporated. Furthermore, the networks were trained on multiple datasets, thereby augmenting the available data, and enabling the generation of images with diverse contrasts obtained from different datasets, given an input image from another dataset. Experimental evaluations conducted on the IXI and BraTS2020 datasets substantiate the efficacy of the proposed method compared to an existing method, as assessed through metrics such as Structural Similarity Index (SSIM), Peak Signal-to-Noise Ratio (PSNR) and Normalized Mean Absolute Error (NMAE). The synthesized images resulting from this method hold substantial potential as invaluable resources for medical professionals engaged in research, education, and clinical applications. Future research gears towards expanding experiments to larger datasets and encompassing the proposed approach to 3D images, enhancing medical diagnostics within practical applications.