Age-specific Risk and Clustering Patterns of Metabolically Unhealthy Status Associated with Obstructive Coronary Artery Disease in Obese and Non-Obese Adults

The burden of metabolic dysfunction and coronary artery disease (CAD) in young adults has rapidly increased. We aimed to investigate whether the association between metabolically unhealthy status and prevalent CAD varies by age in both obese and non-obese individuals, and whether specific metabolic clustering patterns are associated with an elevated likelihood of obstructive CAD among young adults. This hospital-based study involved patients with and without angiographically confirmed obstructive CAD (coronary stenosis ≥ 50