Tricuspid valve infective endocarditis (TVIE) is strongly associated with IV drug use (IVDU); device implants also represent significant risk factors. Congenital anomalies, including ventricular septal defect (VSD), predispose patients to TVIE.1 Streptococcus mitis is a mesophilic alfahaemolytic germ inhabiting the oroand nasopharyngeal cavities and has been implicated in cases of culture-negative endocarditis.2
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