Burnout disproportionately affects healthcare professionals, particularly critical care specialists. The ongoing conflict in Ukraine has placed a significant strain on healthcare resources, with the added burden of the recent COVID-19 pandemic further intensifying the risk of burnout among Ukrainian critical care physicians. This study aimed to evaluate the prevalence of burnout and identify associated risk factors to guide targeted interventions. A cross-sectional survey was conducted from September 2022 to February 2023 among Ukrainian critical care providers recruited via secure messaging Viber™ group chat and the CERTAIN educational platform. The survey captured demographic and practice-related data and employed the Ukrainian-translated Maslach Burnout Inventory (MBI). Statistical analysis comprised descriptive statistics, exact permutation tests, and comparisons to recent European burnout data using risk differences (RDs). Of the 412 individuals who accessed the survey link, 105 critical care physicians submitted survey responses. The prevalence of burnout was 71.4