Cholinergic Α7 Nachr Signaling Suppresses SARS-CoV-2 Infection and Inflammation in Lung Epithelial Cells.

Dear Editor , Coronavirus disease 2019 ( COVID-19) , caused by severe acute respiratory syndrome coronavirus 2 ( SARS-CoV-2) infection, has led to > 6 million deaths and posed a huge threat to the global economy and public health. SARS-CoV-2 enters lung epithelial cells depending on the binding between SARS-CoV-2 S pro-tein and the host receptor angiotensin-converting enzyme 2 ( ACE2) .