Clinicopathologic Characteristics, Treatments, and Survival Outcomes of Early-onset Compared to Later-onset Colorectal Mucinous Adenocarcinomas: A Population-based SEER Analysis.

Colorectal mucinous adenocarcinoma (CMA) is a unique subtype of adenocarcinoma. This study aimed to compare characteristics, treatments, and survival outcomes of early-onset and later-onset CMA. This investigation was a retrospective cohort study from the National Cancer Institute’s SEER Research Data database from 2000 to 2022 on patients with CMA. Patients aged < 50 years (early-onset) and patients aged ≥ 50 years (later-onset) were compared regarding disease characteristics, treatments, and survival. The main outcome measures were 5-year overall survival (OS) and cancer-specific survival (CSS). The study included 55,853 patients; 10.4