Complex Peptides Made Simple

Sean Bartlett,David R. Spring

Nature Chemistry（2016）SCI 1区

Sean Bartlett and David R. Spring are in the Department of Chemistry at the University of Cambridge

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摘要

Nature oxidizes biosynthetic intermediates into structurally and functionally diverse peptides. An iron-catalysed C–H oxidation mimics this approach in the lab, enabling chemists to synthesize structural analogues with ease.

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关键词

Biomimetic synthesis,Synthetic chemistry methodology,Organometallic chemistry,Chemistry/Food Science,general,Analytical Chemistry,Organic Chemistry,Physical Chemistry,Inorganic Chemistry,Biochemistry