Constitutional thinness is a condition characterised bylow body weight, observed from early childhood and persisting into adulthood, with no established organic or functional cause. It is often confused with certain acquired forms of thinness, such as anorexia nervosa. This type of thinness is genetically inheritable. The differential diagnosis is based on the evaluation of weight curves as well as biological and psychometric markers. In terms of diet, affected individuals have a normal energy intake but feel full more quickly. Paradoxically, although they have a positive energy balance, they struggle to gain weight, suggesting anabolic resistance. Constitutional thinness is also associated with osteo-muscular fragility, with reduced bone density and decreased muscle capacity. Therapeutic strategies focus on muscle strengthening and nutritional adjustment, although weight gain is difficult.
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