Correlation of Sample‐to‐cut‐off Ratio of Anti‐sars‐cov‐2 IgG Antibody Chemiluminescent Assay with Neutralization Activity: a Prospective Multi‐centric Study in India

There are limited published data on association of results from commercial serological anti‐SARS‐CoV‐2 IgG antibody CLIA (chemiluminescent immunoassay) assays with neutralizing antibodies. This study was undertaken with an objective to correlate sample‐to‐cut‐off (S/Co) ratio of CLIA antibody tests with inhibition activity, which may then serve as a valuable guide for labelling plasma as COVID convalescent plasma (CCP) for therapy and assessing vaccine efficacy.