Data Supplement from Targeted Deletion and Lipidomic Analysis Identify Epithelial Cell COX-2 As a Major Driver of Chemically Induced Skin Cancer

Epithelial thickness in response to short term DMBA/TPA treatment of Cox-2deltaE mice and their littermate Cox-2fl/fl mice (upper panels), and of Cox-2deltaM mice and their littermate Cox-2fl/fl mice (lower panels). Panels on the left show representative H&E skin sections, panels on the right show quantification of the results. Error bars are SD. * indicates p<0.05.