Decreased Bioavailability of Vitamin D in Obesity.

BACKGROUND:Obesity is associated with vitamin D insufficiency and secondary hyperparathyroidism.OBJECTIVE:This study assessed whether obesity alters the cutaneous production of vitamin D(3) (cholecalciferol) or the intestinal absorption of vitamin D(2) (ergocalciferol).DESIGN:Healthy, white, obese [body mass index (BMI; in kg/m(2)) > or = 30] and matched lean control subjects (BMI 更多