Distinct Size and Spatial Distribution Patterns of ALK-inhibitor-naïve Versus ALK-inhibitor Exposed ALK-positive NSCLC Brain Metastases.

Non-small cell lung cancer (NSCLC) with anaplastic lymphoma kinase rearrangement (ALK+) has a high affinity to form brain metastases (BMs). The cumulative incidence of BMs in ALK + lung cancer is over 50