AbstractPre-requisites to better understand the chapter:knowledge of the major steps and procedures of developing a clinical prediction model.Logical position of the chapter with respect to the previous chapter:in the last chapters, you have learned how to develop and validate a clinical prediction model. You have been learning logistic regression as main algorithm to build the model. However, several different more complex algorithms can be used to build a clinical prediction model. In this chapter, the main machine learning based algorithms will be presented to you.Learning objectives:you will be presented with the definitions of: machine learning, supervised and unsupervised learning. The major algorithms for the last two categories will be introduced.
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