The influence of the fuel Lewis number LeF on Reynolds stresses and their transport during flame–wall interaction (FWI) is studied using a direct numerical simulation database of oblique wall-quenching of V-shaped premixed flames in a turbulent channel flow. Simulations are conducted for LeF=0.6,1.0, and 1.4. Results indicate that LeF significantly affects the magnitude and anisotropy of the Reynolds stresses. In these cases, the location of the FWI is affected by LeF, with the flame at LeF=0.6 interacting closest to the flame holder, while the flame with LeF=1.4 interacts farthest from the flame holder. The wall-normal distributions of the Reynolds stress components deviate significantly from those recorded in the non-reacting turbulent channel flows, with deviations strongly influenced by LeF. The production of the streamwise Reynolds stress component by the mean velocity gradient exceeds sink contributions from other terms, especially downstream of the FWI region. The pressure–strain term plays a dominant role in Reynolds stress transport in the spanwise direction, facilitating Reynolds stress redistribution. In particular, local equilibrium between the generation and dissipation of Reynolds stresses is not achieved, particularly as LeF decreases, leading to anisotropy of Reynolds stresses. These findings highlight the impact of LeF on near-wall flow dynamics and the production, redistribution, and dissipation of Reynolds stresses. The study provides valuable information for improving turbulence models for Reynolds-averaged Navier–Stokes simulations of FWIs under varying LeF conditions, advancing the understanding of turbulent boundary layer flows with premixed flames.