Abstract SCAN-C is a lightweight block cipher featuring a hybrid Feistel-SPN structure designed for Controller Area Network (CAN) security. This work presents the first full-round differential cryptanalysis of SCAN-C, demonstrating that its unique XNOR-based key mixing provides no additional security margin. We also prove that XNOR-based mixing is structurally equivalent to standard XOR mixing, as the corresponding difference distribution tables (DDTs) differ only by a permutation of indices. Utilizing an SMT-based automated search, we identify optimal differential clusters, including a 9-round distinguisher with a probability of $$2^{-51.30}$$ 2 - 51.30 . By extending these results, we show that the complete internal key state can be recovered through the recovery of all 12 round keys, requiring around $$2^{55}$$ 2 55 chosen plaintexts and $$2^{69}$$ 2 69 encryptions. Our results confirm that the current 12-round specification is insufficient for security and is the first to show that differential cryptanalysis is equivalent under both XOR and XNOR difference definitions.