Exome Sequencing of Multiple Affected Individuals from an Irish Family with Brugada Syndrome Uncovers A Novel Locus for the Disorder

P2289 | BENCH Exome sequencing of multiple affected individuals from an Irish family with Brugada Syndrome uncovers a novel locus for the disorder J.G. Barc1, R.F. Marsman1, S. Le Scouarnec2 , Y. Mizusawa1, A.V. Postma3, N. Carter2, R. Redon4, A.A.M. Wilde1, P. Mckeown5, C.R. Bezzina1. 1Academic Medical Center, Heart Failure Research Center, Department of Experimental Cardiology, Amsterdam, Netherlands; 2Wellcome Trust Sanger Institute, Cambridge, United Kingdom; 3Academic Medical Center, Heart Failure Research Center, Dept. of Anatomy, Embryology and Physiology, Amsterdam, Netherlands; 4INSERM UMR1087 CNRS UMR 6291, l’Institut du Thorax, University Hospital of Nantes, Nantes, France; 5Queen’s University Belfast, Dentistry and Biomedical Sciences, Belfast, United Kingdom