Green Functionalization of Silver Nanoparticles Using Leaf Extract of Cymbopogon Citratus and Assessment of Their Biological Activities

In present study, silver nanoparticles (AgNPs) were produced by employing a "green" biosynthetic method using leaf extract of Cymbopogon citratus (CCLE). The reaction between CCLE and silver nitrate produced black coloured solution inferred as the visual confirmation of nanoparticle synthesis. The UV-visible spectrum of spherical oval shaped CCLE-AgNPs reported absorbance at 420 nm with FCC crystalline lattice confirmed by XRD. The average size of CCLE-AgNPs was reported as 30.6 nm (XRD) and 13.1-30.9 nm (TEM) along with the elemental composition by EDX evaluated to be 10.79 %. The presence of numerous organic metabolites was confirmed by FTIR and validated by GC-MS inferring diverse types of organic metabolites as capping and reducing mediators. The bioactivities reported were: antibacterial (MIC and MBC ranged from 15 to 35 mu g/ml against both Gram + and - cells); anti-biofilm (70-82 %); antidiabetic (76-83 %); and anti-inflammation (60-65 %). The dye degradative kinetics of CCLE-AgNPs against dyes Rhodamine B and Methyl orange followed pseudo-first order reaction rate with % efficiency of 93 % and 95 %, respectively. Thus, our results explicated a quick, environmentally inert, economical method for CCLE-AgNPs amalgamation for viable applications as prospective nanomedicines and nanocatalysts.