Even though HIV-TB co-infection is an emerging public health issue among migrants in European countries, the number of related articles has shown a decreasing trend. To better estimate the extent of this problem, we analyzed 34 articles reporting both prevalence and odds ratio for HIV-TB co-infection in migrants in European countries. Heterogeneity analysis was conducted to assess potential bias, and a random-effects model was used to calculate the effect size. The overall prevalence of HIV-TB co-infection was 9