Human Leukocyte Antigen Genotype, Body Mass Index Status, and Young-Adult-onset Type 1 Diabetes

Cole D. Bendor,Aya Bardugo,Amir Tirosh, Sapir Israeli,Estela Derazne,Inbar Zucker, Miri Lutski,Tali Cukierman-Yaffe,Ariel Furer, Zivan Aviad Beer,Orit Pinhas-Hamiel,Gabriel Chodick, Bracha Zisser,Arnon Afek,Hertzel C. Gerstein, Sigal Manor,Yoram Louzoun,Gilad Twig

Cardiovascular diabetology（2026）SCI 1区SCI 2区

Israel Defense Forces Medical Corps

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摘要

Obesity is increasingly recognized as a risk factor not only for type 2 diabetes but also for type 1 diabetes. We assessed its interaction with genetic susceptibility in the risk for adult-onset type 1 diabetes. We conducted a population-based retrospective cohort study of 604,968 Israeli adolescents (aged 16–19 years; 44

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关键词

Type 1 diabetes,Overweight,Obesity,HLA,Genetic

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