Ideal Alveolar Air and the Analysis of Ventilation Perfusion Relationships in the Lungs

ARTICLES‘Ideal’ Alveolar Air and the Analysis of Ventilation-Perfusion Relationships in the LungsR. L. Riley, and A. CournandR. L. Riley, and A. CournandPublished Online:01 Jun 1949https://doi.org/10.1152/jappl.1949.1.12.825MoreSectionsPDF (3 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInEmailWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformationCited ByUsing pulmonary gas exchange to estimate shunt and deadspace in lung disease: theoretical approach and practical basisPeter D. Wagner, Atul Malhotra, and G. Kim Prisk15 April 2022 | Journal of Applied Physiology, Vol. 132, No. 4Blood gas analyses in hyperbaric and underwater environments: a systematic reviewMatteo Paganini, Richard E. Moon, Nicole Boccalon, Giorgio E. M. Melloni, Tommaso A. Giacon, Enrico M. Camporesi, and Gerardo Bosco25 January 2022 | Journal of Applied Physiology, Vol. 132, No. 2Ideal alveolar gas defined by modal gas exchange in ventilation-perfusion distributionsPhilip J. Peyton10 December 2021 | Journal of Applied Physiology, Vol. 131, No. 6i stands for internet (and other things), not for inspired O2 concentrationPeter D. Wagner22 March 2021 | American Journal of Physiology-Lung Cellular and Molecular Physiology, Vol. 320, No. 3Measuring the efficiency of pulmonary gas exchange using expired gas instead of arterial blood: comparing the “ideal” Po2 of Riley with end-tidal Po2John B. West, Matthew A. Liu, Phoebe C. Stark, and G. Kim Prisk28 July 2020 | American Journal of Physiology-Lung Cellular and Molecular Physiology, Vol. 319, No. 2Deriving the arterial Po2 and oxygen deficit from expired gas and pulse oximetryG. Kim Prisk and John B. West14 October 2019 | Journal of Applied Physiology, Vol. 127, No. 4Noninvasive measurement of pulmonary gas exchange: comparison with data from arterial blood gasesJohn B. West, Daniel L. Wang, G. Kim Prisk, Janelle M. Fine, Amy Bellinghausen, Matthew Light, and Daniel R. Crouch18 December 2018 | American Journal of Physiology-Lung Cellular and Molecular Physiology, Vol. 316, No. 1A mathematical model of CO2, O2 and N2 exchange during venovenous extracorporeal membrane oxygenation9 August 2018 | Intensive Care Medicine Experimental, Vol. 6, No. 1A New, Noninvasive Method of Measuring Impaired Pulmonary Gas Exchange in Lung Disease: An Outpatient StudyChest, Vol. 154, No. 2Human Cognitive Limitations. Broad, Consistent, Clinical Application of Physiological Principles Will Require Decision SupportAnnals of the American Thoracic Society, Vol. 15, No. Supplement_1Understanding blood gas analysis11 May 2017 | Intensive Care Medicine, Vol. 44, No. 1Alcohol breath test: gas exchange issuesMichael P. Hlastala and Joseph C. Anderson1 August 2016 | Journal of Applied Physiology, Vol. 121, No. 2Ventilation, Blood Flow, and Gas ExchangeCombined effects of inspired oxygen, carbon dioxide, and carbon monoxide on oxygen transport and aerobic capacityGeorge H. Crocker, Balazs Toth, and James H. Jones1 September 2013 | Journal of Applied Physiology, Vol. 115, No. 5LiteraturEffect of a patent foramen ovale on pulmonary gas exchange efficiency at rest and during exerciseAndrew T. Lovering, Michael K. Stickland, Markus Amann, Matthew J. O'Brien, John S. Hokanson, and Marlowe W. Eldridge1 May 2011 | Journal of Applied Physiology, Vol. 110, No. 5Mechanical Ventilation During General AnesthesiaBaseline BAL Neutrophilia Predicts Early Mortality in Idiopathic Pulmonary FibrosisChest, Vol. 133, No. 1Understanding pulmonary gas exchange: ventilation-perfusion relationshipsJohn B. West1 December 2004 | American Journal of Physiology-Lung Cellular and Molecular Physiology, Vol. 287, No. 6Understanding pulmonary gas exchange: ventilation-perfusion relationshipsJohn B. West1 November 2004 | Journal of Applied Physiology, Vol. 97, No. 5The effect of pulmonary fibrosis on survival in patients with hypersensitivity pneumonitisThe American Journal of Medicine, Vol. 116, No. 10A Century of Pulmonary Gas ExchangeAmerican Journal of Respiratory and Critical Care Medicine, Vol. 169, No. 8Changes in Clinical and Physiologic Variables Predict Survival in Idiopathic Pulmonary FibrosisAmerican Journal of Respiratory and Critical Care Medicine, Vol. 168, No. 5Idiopathic Pulmonary FibrosisAmerican Journal of Respiratory and Critical Care Medicine, Vol. 167, No. 7ATS/ACCP Statement on Cardiopulmonary Exercise TestingAmerican Journal of Respiratory and Critical Care Medicine, Vol. 167, No. 2Ventilation-perfusion ratio of signal intensity in human lung using oxygen-enhanced and arterial spin labeling techniques31 July 2002 | Magnetic Resonance in Medicine, Vol. 48, No. 2Nitric oxide inhalation increases alveolar gas exchange by decreasing deadspace volumeCritical Care Medicine, Vol. 29, No. 6Components of an Effective Medical Simulation Software Solution18 August 2016 | Simulation & Gaming, Vol. 32, No. 2Pulmonary gas-exchange analysis by using simultaneous deposition of aerosolized and injected microspheresWilliam A. Altemeier, H. Thomas Robertson, and Robb W. Glenny1 December 1998 | Journal of Applied Physiology, Vol. 85, No. 6My affair with the JAPRobert F. Forster1 July 1998 | Journal of Applied Physiology, Vol. 85, No. 1Cardiopulmonary effects of enoximone or dobutamine and nitroglycerin on mitral valve regurgitation and pulmonary venous hypertensionJournal of Cardiothoracic and Vascular Anesthesia, Vol. 11, No. 4The Ventilation-Perfusion Relation and Gas Exchange in Mitral Valve Disease and Coronary Artery Disease Implications for Anesthesia, Extracorporeal Circulation, and Cardiac SurgeryAnesthesiology, Vol. 86, No. 4Efficacy of perfluorocarbon partial liquid ventilation in a large animal model of acute respiratory failureCritical Care Medicine, Vol. 24, No. 7Partial liquid ventilation provides effective gas exchange in a large animal modelJournal of Critical Care, Vol. 11, No. 1Respiratory dysfunction after uncomplicated cardiopulmonary bypassThe Annals of Thoracic Surgery, Vol. 56, No. 5Coronary perfusion pressure, end-tidal C02 and adrenergic agents in haemodynamic stable ratsResuscitation, Vol. 25, No. 3The design and implementation of a ventilator-management advisorArtificial Intelligence in Medicine, Vol. 5, No. 1Applied aspects of pulmonary gas exchangeCurrent Anaesthesia & Critical Care, Vol. 1, No. 1Panting in Dogs as a Model for High-Frequency Ventilation1 December 2016 | Engineering in Medicine, Vol. 17, No. 4The effect of blood flow and diffusion impairment on pulmonary gas exchange: A computer modelComputers and Biomedical Research, Vol. 20, No. 5A flight simulator for general anesthesia trainingComputers and Biomedical Research, Vol. 20, No. 1THE OXYGEN SECRETION CONTROVERSYThe Lancet, Vol. 327, No. 8482A mathematical model for gas exchange in the fish gill based on non-linear blood gas equilibrium curvesRespiration Physiology, Vol. 62, No. 3Pulmonary gas exchange during high-frequency ventilation in dogsRespiration Physiology, Vol. 54, No. 1The pulmonary vasculature of the mountain-viscacha (Lagidium peruanum). The concept of adapted and acclimatized vascular smooth muscleJournal of Comparative Pathology, Vol. 91, No. 2A pocket calculator program for non-invasive bedside assessment of cardiorespiratory functionComputers in Biology and Medicine, Vol. 10, No. 3Blood/gas equilibrium of carbon dioxide in lungs. A critical reviewRespiration Physiology, Vol. 39, No. 1Distributions of V̇A/Q̇ in dog lungs obtained with the 50 compartment and the log normal approachRespiration Physiology, Vol. 38, No. 3How to be less invasiveThe American Journal of Medicine, Vol. 67, No. 1Theoretical analysis of independent V̇a and Q̇ inequalities upon pulmonary gas exchangeRespiration Physiology, Vol. 29, No. 2Variations in pulmonary gas exchange due to changes in pulmonary artery pressure and flowJournal of Surgical Research, Vol. 18, No. 4Acid-base balance and blood gases in prognosis and therapy of congenital diaphragmatic herniaJournal of Pediatric Surgery, Vol. 9, No. 1Pulmonary function with acute loss of excess lung water by hemodialysis in patients with chronic uremiaThe American Journal of Medicine, Vol. 55, No. 2Mathematical Models and Their Applications in Medicine25 June 2016 | Scottish Medical Journal, Vol. 17, No. 12Inhomogeneity effects on O2 and CO pulmonary diffusing capacity estimates by steady-state methods. TheoryRespiration Physiology, Vol. 13, No. 1The effect of oxygen administration on gas exchange and cardiopulmonary function in normal subjectsRespiration Physiology, Vol. 12, No. 3The lung in shockThe American Journal of Cardiology, Vol. 26, No. 6Influence of the cyclical pattern of ventilatory flow on pulmonary gas exchangeRespiration Physiology, Vol. 10, No. 3Reliability of blood PCO2, measurements by the CO2-electrode, the whole-blood CCO2/pH method and the astrup methodRespiration Physiology, Vol. 10, No. 1Determinants of the physiological systems responses to muscular exercise in healthy subjectsVentilation-perfusion inequality and overall gas exchange in computer models of the lungRespiration Physiology, Vol. 7, No. 1Pulmonary diffusing capacity at basal and increased O2 uptake levels in anesthetized dogsRespiration Physiology, Vol. 6, No. 2Cirrhosis, cyanosis and polycythaemia: Multiple pulmonary arteriovenous anastomosesThe American Journal of Medicine, Vol. 45, No. 1Computer program for the production of O2-CO2 diagramsRespiration Physiology, Vol. 4, No. 2Chronic obstructive bronchopulmonary diseaseThe American Journal of Medicine, Vol. 44, No. 1Effects of ventilation-perfusion inequality on elimination of inert gasesRespiration Physiology, Vol. 3, No. 1PATTERNS OF RESPIRATORY INSUFFICIENCYThe Lancet, Vol. 287, No. 7439Theory of an inert gas method for regional pulmonary blood flow in bronchospirometryRespiration Physiology, Vol. 2, No. 1Calculation of certain indices of cardio-pulmonary function using a digital computerRespiration Physiology, Vol. 1, No. 3SEVERITY OF RESPIRATORY FAILURE ARTERIAL BLOOD-GASES IN UNTREATED PATIENTSThe Lancet, Vol. 285, No. 7381SAFETY OF DRUGSThe Lancet, Vol. 281, No. 7288HYPOXIC HYPOXÆMIA AFTER HÆMORRHAGE AND IN SHOCKThe Lancet, Vol. 281, No. 7288Effect of induced pneumothorax on the pulmonary shunt and the ventilation in a patient with atelectasis of the lungThe American Journal of Medicine, Vol. 31, No. 6Pulmonary function in the Hamman-Rich syndromeThe American Journal of Medicine, Vol. 29, No. 6Pulmonary Diffusion of Carbon Dioxide5 August 2002 | Physics in Medicine and Biology, Vol. 5, No. 2Pulmonary alveolar proteinosisThe American Journal of Medicine, Vol. 28, No. 3RESPIRATORY FAILUREThe Lancet, Vol. 275, No. 7114A peculiar type of cardiopulmonary failure associated with obesityThe American Journal of Medicine, Vol. 21, No. 5The interrelationships of ventilation, circulation and metabolismThe American Journal of Medicine, Vol. 19, No. 4Respiratory and Circulatory Studies of Patients with Mitral StenosisCirculation, Vol. 8, No. 6Pulmonary function in sarcoidosisThe American Journal of Medicine, Vol. 15, No. 4Pulmonary function in patients convalescing from acute poliomyelitis with respiratory paralysisThe American Journal of Medicine, Vol. 12, No. 4Clinical and physiologic features of some types of pulmonary diseases with impairment of alveolar-capillary diffusionThe American Journal of Medicine, Vol. 11, No. 6Pulmonary fibrosis and respiratory functionThe American Journal of Medicine, Vol. 10, No. 5Physiopathologic aspects of chronic pulmonary emphysemaThe American Journal of Medicine, Vol. 10, No. 4Interpretation of commonly used pulmonary function testsThe American Journal of Medicine, Vol. 10, No. 3Effect of ACTH in chronic lung diseaseThe American Journal of Medicine, Vol. 10, No. 2Pulmonary gas exchangeThe American Journal of Medicine, Vol. 10, No. 2 More from this issue > Volume 1Issue 12June 1949Pages 825-847 https://doi.org/10.1152/jappl.1949.1.12.825PubMed18145478History Published online 1 June 1949 Published in print 1 June 1949 Metrics Downloaded 2,761 times