Эндотелиопротективные, Кардиопротективные Эффекты Аторвастатина И Его Комбинаций С L-аргинином И Резвератролом В Эксперименте

At the laboratory of the Cardiofarmacology Scientific Research Institute of Ecological medicine endothelioprotective, cardioprotective activity of inhibitor of 3-gidroksi-3-metilglutaril-CoA reductase simvastatin and its combinations with L-arginin and resveratrol were investigated in experiments on rats. The received results have shown the presence of expressed endothelioprotective effects, amplifying with additional introduction of L-arginin and resveratrol at simvastatin The most expressed correction of endothelial dysfunction is observed in application of simvastatin in a combination with L-arginin. Warm loading tests have revealed more expressed cardioprotective activity of simvastatin, in comparison with its combinations with L-arginin and resveratrol.