Longitudinal Trends of Intraocular Lens Dislocation in a Federated Electronic Health Record Network.

BACKGROUND AND OBJECTIVE:The aim of this study was to characterize longitudinal trends in intraocular lens (IOL) dislocation in patients after cataract surgery. PATIENTS AND METHODS:Using the TriNetX network, a retrospective cohort study was conducted of 866,010 patients who underwent cataract surgery from the years 2000 to 2024. Those patients who had experienced IOL dislocation based on International Classification of Diseases, Ninth and Tenth Revision (ICD-9 and -10) codes were identified. Patients with risk factors for IOL dislocation, such as ocular trauma, prior intravitreal injections, prior pars plana vitrectomy, pseudoexfoliation glaucoma, and Marfan syndrome, based on ICD-9/-10 and Current Procedural Terminology (CPT) codes, were also identified. RESULTS:From 2020 to 2024, 9,929 (1.1%) of the 866,010 patients experienced IOL dislocation. Over the past 2 decades, there was a significant monotonic increase in the incidence rate of IOL dislocation (P < .01), as well as ocular trauma (P < .01), intravitreal injections (P < .01), and pars plana vitrectomy (P < .01). CONCLUSION:IOL dislocation is becoming increasingly common. Practitioners must be prepared to manage these conditions.