A chromatographic process may operate continuously if there is relative motion between the stationary (absorbent) phase and the point where the feed is introduced into that phase. Under these circumstances, component column residence time differences are transformed into physical displacements so that each feed component may be withdrawn continuously at a fixed and characteristic distance away from the feed point. The objective of this work is to model the continuous separation on the rotating annular chromatograph and to compare model and experimental data. A simulation model of the rotating annulus separation of a binary mixture has been developed. The steady-state chromatographic cycle is considered as the successive application of the saturation and elution processes. The equations developed are complicated by considering the effects of interaction between the two solutions. Experimental data are obtained from the separation of the isomers, glucose and fructose.