This work investigates video encoding parallelization techniques based on the VVC standard, using the open and optimized encoder software implementation VVenC. Modern multi-processor systems offer significant opportunities for accelerating video encoding. By employing a proposed combination of parallelization methods, the VVenC encoder achieves an acceleration factor of up to 22 compared to single-threaded mode on a 32-core system, with potential increases to 27x at higher bitrates. Building upon prior work on inter-frame parallelization (IFP), the study introduces frame region-based synchronization, enabling further acceleration of up to 10%. Beyond that, the study demonstrates extending frame parallelization beyond Group of Pictures (GOP) boundaries, which improves IFP speed up by 37% and 11% at HD and UHD resolutions, respectively. Additional combinations with other VVC parallelization tools, such as tiles and VVC Wavefront Parallel Processing (WPP), are also explored. The paper provides a comprehensive analysis of parallelization challenges and highlights areas for further improvement.