In order to study the influence of tuyere structure parameters on the gas flow distribution of oxygen blast furnace (OBF), a three-dimensional full-scale CFD mathematical model is established based on the internal model parameters of 430 m³ OBF of Bayi Steel. Without changing the structural parameters of the hearth tuyere and the blast parameters, the influence laws of tuyere area, tuyere number and tuyere angle on the gas flow distribution are analyzed, and five evaluation indicators, namely D, H, V Horizontal, V Vertical and V Depth , are put forward for the initial gas flow of the shaft tuyere to evaluate the gas distribution state. The results show that increasing tuyere number or decreasing tuyere area can significantly enhance the gas velocity at the upper part of OBF and effectively improve the reducing atmosphere, but the shaft tuyere angle has little effect on the gas velocity. The structural parameters of tuyere mainly affect the initial gas flow pattern. Reducing tuyere diameter from 100 mm to 80 mm can form a more penetrating concentrated gas flow, and its velocity attenuation depth D is reduced from 0.23 m to 0.17 m. However, if the tuyere angle is increased from 3 to 7, the gas flow will penetrate downwards, which will expand the low-speed area at the lower part of tuyere. The five evaluation indicators put forward in this study can effectively quantify the initial gas flow characteristics, and provide an important theoretical basis for the optimization of shaft tuyere structure of OBF.