To evaluate the long-term results of transhepatic treatment of portal vein complications (PVCs) after pediatric liver transplantation (PLTx) at a single center. All interventional procedures for PVCs after PLTx performed between 2005 and 2023 were retrospectively analyzed. Clinical signs of portal hypertension and portal vein (PV) flow velocity on Doppler ultrasound were routinely assessed during follow-up. Primary patency, assisted primary patency, and survival rates were evaluated. Out of 275 consecutive PLTs, 26 children (median age 19.8 months, range: 8.5–154.1) underwent 39 endovascular procedures for PVCs. Technical success was achieved in 97