The study aimed to assess the prevalence and severity of post-traumatic stress disorder (PTSD) among Aksum City Massacre Survivors in Tigray, Ethiopia. Using a community-based cross-sectional design, data were collected from 439 participants with the PCL-5 scale. Statistical analyses were conducted in SPSS version 26 using descriptive and inferential methods, including means, standard deviations, frequencies, percentages, independent-sample t-tests, and ANOVA. Results showed a high prevalence (58.5%) and severe levels (40.3%) of PTSD among the survivors. No significant differences were found across sex, age, or educational status. The findings highlight an urgent need for collaborative interventions and resource mobilization to address the severe mental health challenges faced by this population.