PURPOSE: To provide a robot system for operation which has a manipulator arm which is provided with a tool for operation and a degree of multiple movement freedom. CONSTITUTION: A manipulator arm 14 which is provided with a tool for operation 22 and has a degree of multiple movement freedom includes a safety monitoring and processing device 38 which is connected with a controller 24 to position the tool for operation in such a manner that it can be controlled and determines a position of the tool for operation in a three-dimensional coordinate system. Furthermore, an output for turning a space region including at least a part of the manipulator arm into a picture image is connected with a processing device 38 which processes quantitative model to determine whether the tool for operation is positioned on the outside of the quantitative model or not. Furthermore, it includes a strain gage 40 for detecting the slide between an immobilized tissue such as a bone and a reference point 44 three- dimensionally.