Sea clutter significantly impacts radar maritime target detection. Existing methods still show limited clutter suppression performance, and their generalization ability re quires further improvement. To address this issue, a sea clutter suppression method based on the pyramid multi-scale residual attention generative adversarial network (PMS-RA GAN) is proposed. In the generator, an integrated residual attention mechanism (IRAM) is designed to highlight the target and effectively suppress the background clutter. Furthermore, a multi-scale pyramid adaptive feature extraction (MPA) module based on sea clutter characteristics is designed to generate high quality radar time-frequency images. Additionally, a composite loss function is proposed to balance between image quality and detail performance. Experimental results on real world datasets demonstrate that PMS-RA GAN outperforms the existing methods in sea clutter suppression, significantly improving target detection performance. The complete code for the proposed PMS-RA GAN model is publicly available at https://github.com/202400358077/PMS-RA-GAN and archived on Zenodo at https://zenodo.org/records/19805662.