Abstract This chapter describes several important concerns that either address unanswered questions about the Critical Time Intervention (CTI) model itself or bear on issues related to future adaptation and scale-up. These include the need to validate essential elements of the model via so-called dismantling studies; examination of how to best target the program in order to maximize effectiveness and efficiency; evaluating cost-effectiveness, ideally addressing both individual- and system-level benefits; and specifying ways in which CTI can best complement related intervention models such as permanent supportive housing and Assertive Community Treatment. The chapter also considers workforce issues, including greater use of persons with lived experience as CTI workers and supervisors; strategies for effectively delivering CTI via remote technology; and how CTI can be adapted for use in resource-scarce settings such as the Global South. It then identifies several unanswered research questions and considers important issues related to long-term sustainment of the model. The chapter concludes with a discussion of resources and strategies needed to ensure long-range model sustainment.
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