Abstract The Prologue sets the scene and tone for the book by introducing readers to the work’s main character: the India-built British merchant vessel, the Edwin Fox. It then establishes the major themes of the work, explaining how it tells the story of globalization between the years 1850 and 1914 through the voyages of a single, work-a-day merchant vessel. It contends that a microhistorical approach to the history of globalization highlights the local and human agency at work and creates opportunities to explore the myriad complexities and the intimate and unexpected interconnections that really were the stuff of globalization. The Prologue also situates the work within the relevant historiography and provides a brief overview of the book’s structure.