We introduce Simulation-Based Imaging (SBI), a framework for non-destructive acoustic imaging in which machine learning models trained entirely on simulated data serve as real-time solvers for the acoustic inverse problem. A high-fidelity nodal Discontinuous Galerkin forward solver generates large training datasets by randomizing inclusion geometry within a unit-cube domain; a 2D convolutional neural network then learns a direct mapping from boundary pressure measurements to a 32 by 32 by 32 voxel reconstruction of the interior. The trained model reliably recovers inclusion position and size from 144 boundary sensors with no prior knowledge of inclusion count or geometry. Reconstruction error degrades by only 13