Purpose. The results of primary percutaneous coronary interventions (PPCI) in the treatment of ST elevation myocardial infarction (STEMI) patients with coronary artery disease (CAD) and peripheral arterial disease (PAD) remain little known. Materials and methods. We analyzed 12-month outcomes of 259 consecutive patients who underwent PPCI with STEMI. The outcomes of 48 patients (18,5 %) with CAD and PAD (CAD + PAD group), who underwent PPCI, were compared with the outcomes of 211 patients (81,5 %) with isolated CAD and without PAD (CAD group), who underwent PPCI. The groups were comparable regarding the incidence of diabetes mellitus, arterial hypertension, smoking and left ventricular ejection fraction. The endpoints at 12 months included all deaths, myocardial infarction (MI), target lesion/vessel revascularization (TLR/TVR) and non target vessel revascularization (non-TVR). Results. Angiographic success (TIMI III flow and residual stenosis < 20 % by QCA) was 93,8 % for CAD + PAD group (n = 45) and 97,2 % for CAD group (n = 205) (р = 0,486). At 12 months CAD + PAD group and CAD group did not differ in the incidence of death (8,3 vs 6,2 % respectively, p = 0,821), TLR/TVR (6,3 vs 2,8 % respectively, p = 0,468), while there were differences in the rates of nonfatal MI (20,8 vs 9 % respectively, p = 0,036) and non-TVR (37,5 vs 16,6 % respectively, p = 0,002). Conclusion. ST-elevation myocardial infarction patients with peripheral arterial disease are a special category of patients having significantly more severe coronary artery stenoses, higher incidence of non-fatal myocardial infarctions and higher incidence of non-target vessel revascularizations during 12 months.
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