Studies of Transplanted Haematopoietic Tissue Utilizing a Modified Algire Back Chamber. I. Vasoproliferation Following Erythropoietin Stimulation.

In vivo microscopic observations of splenic tissue transplanted into modified Algire back chambers in mice revealed increased vascularity of the transplant following injections of various doses of erythropoietin. Concomitant histologic and peripheral blood studies suggested that this was vasoproliferation that occurred independent of the process of erythropoiesis.