Supplementary Figure 3 shows differential abundance and pathway enrichment analyses of clusters. (A) Volcano plot displaying the differentially expressed proteins between PDA samples classified between groups 1 and 3 against groups 2 and 4. (B) Pathways enriched in KEGG, Reactome, and Wikipathways for proteins upregulated in samples from clusters 2 and 4 compared to clusters 1 and 3.