Supplementary Figure 6 from Spatial and Single-Cell Analyses Reveal Heterogeneity of DNAM-1 Receptor–Ligand Interactions That Instructs Intratumoral Γδt-Cell Activity

Supplementary Figure 6 The cell-cycle scores and expression of functional genes in tumor cells and γδT cells in spatial transcriptome analysis and scRNA sequencing analysis. (A) Cell-cycle score analysis of tumor cells in spatial transcriptome analysis. (B) Spatial distribution and expression of proliferating markers. (C) Cell-cycle score analysis of tumor cells in scRNA sequencing analysis. (D) Violin plots showing the expression levels of neuroblastoma related genes in tumor cells in scRNA sequencing analysis. (E) and (F) Cell-cycle score and GSVA score analysis of γδT cells in scRNA sequencing analysis. (G) Violin plots showing the expression levels of DNAM-1, TIGIT, CD96, PD-1, TIM-3, IFN-γ, granzyme B and perforin in γδT cells in scRNA sequencing analysis.