Supplementary Figure S17 from A Prognostic Signature for Lung Adenocarcinoma in Patients Who Have Never Smoked

Supplementary Figure S17 shows Kaplan-Meier (KM) survival curves for relapse-free survival stratified by NS-LUAD expression subtypes in (A) patients with stage IA tumors, (B) patients with stage I tumors harboring no EGFR mutations or ALK fusions, or with no clinical records indicating treatment with tyrosine kinase inhibitor (non-TKI subset). P-values and hazard ratios (HR) were calculated using Cox proportional hazards models adjusted for age and sex. The number of samples in each subgroup is indicated on the KM curves. Unless otherwise specified, p-values are based on 10-year overall survival; for comparisons involving the chaotic subtype, 5-year overall survival rates were used owing to its association with advanced tumor stage. For the non-TKI subset, comparisons between the chaotic and steady subtypes were based on 10-year overall survival due to the absence of death events within the 5-year time window.