Synthesis, Crystal Structure and Hirshfeld Surface Analysis of 3-[5-(4-Chlorophenyl)-2-sulfanylidene-1,3,4-oxadiazol-3-yl]-3-(4-methylphenyl)-1-(thiophen-2-yl)propan-1-one

The title thiophene-chalcone derivative, C 22 H 17 ClN 2 O 2 S 2 , contains a planar oxadiazole, a thiophene and two phenyl rings. The dihedral angle between the oxadiazole and thiophene rings is 27.45 (10)°, and they are oriented with respect to the chlorophenyl and methylphenyl rings at 22.61 (10), 67.07 (8) and 49.16 (10), 87.22 (8)°, respectively, while the phenyl rings are oriented at 51.78 (9)°. In the crystal, π–π stacking interactions and C—H...π(ring) interactions help to consolidate the packing. Hirshfeld surface analysis revealed that the most important contributions to the crystal packing are from H...H (31.6%), H...C/C...H (20.0%), H...S/S...H (14.2%) and H...O/O...H (9.5%) interactions.