The cover picture shows a 2,2,2-trifluoroethyl oxalate derivative utilized by Enamine scientists in a one-pot parallel synthesis of aliphatic oxamides. The developed procedure provides synthetic and medicinal chemists with a facile route to large collections of compounds bearing the oxamide motif. Details are discussed in the article by Y. S. Moroz, P. K. Mykhailiuk et al. on p. 2120 ff. This cover is dedicated to the 25th anniversary of Enamine Ltd.
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