Two T(9;22) Leukemia Cell Lines (NALM-24 and NALM-25) with Bi-Phenotypic Characteristics and an EBV-positive B-cell Non-Leukemia Cell Line (B262) Established from a Patient with Acute Lymphoblastic Leukemia.

Based on the immunophenotypic, cytogenetic and genotypic findings, two unique leukemia cell lines, NALM-24 and NALM-25, and an EBV-transformed "normal" B-lymphoblastoid cell line (B262) from a patient with ALL were established and characterized. NALM-24 and NALM-25 are unique in that expression of both show B cell and myeloid cell features with the t(9;22) chromosome in single clonal leukemic cell populations.