This themed issue of the Journal of Visual Culture is concerned with how to think and work across what might at first sight seem to be incommensurate worlds. The articles assembled here think through questions of evidence, affect and speculation, and how these operate within our current economy of knowledge production through the use of practices such as mapping, modelling, sensing and storytelling. While these practices are not new, they have been transformed through advancements in technology and through the way they are embedded within the digital realm. In attending to these practices, the authors give precedence to different ways of knowing the world, to other forms of intelligence, and demonstrate a commitment to developing forms of practice that weave together what might be contradictory positions into future scenarios.