The utility model provides a vertical processing lathe guide device. Vertical processing lathe guide device includes: a top plate; the two L-shaped supporting legs are fixedly arranged at the bottom of the top plate and are symmetrically arranged; the mounting plate is arranged between the two L-shaped supporting legs, and two sides of the mounting plate are fixedly connected with the two L-shaped supporting legs respectively; the rodless cylinder is fixedly arranged at the top of the mounting plate; the rectangular through hole is formed in the top of the top plate; and the movable carrier plate is slidably arranged in the rectangular through hole, and the bottom of the movable carrier plate extends to the lower part of the top plate and is fixedly connected with the rodless cylinder output block. The utility model provides a vertical processing lathe guide device has security, convenient to use's that improves operating personnel operation advantage.