专

一种抗菌丹参酮提取物、其制备方法、用途及其产品

KR08737882B2

发明人

钟忠

受让人

BOZHONG SHENGJING MEDICAL TECH

申请人

Byung-lyul Park, Gil-heyun Choi, Pil-kyu Kang, Dae-lok Bae, Dong-kak Lee

申请号

102477

申请日

1992-09-18

公开(公告)号

KR08737882B2

公开(公告)日

2007-09-26

IPC分类号

B21D039/20A44B019/46B21D039/08A44B019/42A41H037/06B21D053/54

CPC分类号

优先权号

3923077

优先权日

1977-09-19

摘要

The system includes a light source (1) e.g. a fluorescent tube, surrounded by a reflector (2) which directs the light emitted along a direction (x). The reflector has the shape of a compound parabolic concentrator and cooperates with a glass waveguide (3).

The wave guide lower extremity presents a micro-prism structure (4) which reflects the incident light along a direction (z). The structure surface is covered by an aluminium layer (5). The opposite extremity of the waveguide is provided with a collimator (6,8).

USE -For TV, videophone, etc.

ADVANTAGE -Is easy to manufacture, with simplified structure and generates strongly collimated light.

权利要求

1. An adjustable support frame for supporting a display screen on a supporting surface, the display screen having a screen back and a screen bottom, said support frame comprising: a frame base adapted to be disposed on the supporting surface; a bottom-supporting strut unit having a lower end connected fixedly to said frame base, and an upper end adapted to be connected pivotally to the screen bottom; a back-supporting strut unit including a connecting member and a supporting member, the supporting member having a lower end connected pivotally to said frame base, and an upper end connected pivotally to said connecting member; and an adjusting unit including a mounting plate adapted to be attached fixedly to the screen back and having a slide slot, said connecting member being movable along said slide slot, a first engaging member disposed fixedly on said mounting plate, a second engaging member disposed movably on said mounting plate, a driving member disposed movably on said mounting plate and movable on said mounting plate between a locking position and a release position, wherein said second engaging member engages said first engaging member to lock said connecting member on said mounting plate and angle adjustment of the display screen is prevented when said driving member is disposed at the locking position, and said second engaging member is removed from said first engaging member to release said connecting member from said mounting plate and angle adjustment of the display screen is allowed when said driving member is disposed at the release position, and a biasing unit for biasing said driving member to said locking position.

2. The adjustable support frame as claimed in claim 1 , wherein said mounting plate has opposite front and rear side surfaces, said connecting member having a front side surface abutting against said rear side surface of said mounting plate and formed with a fixed guiding projection unit extending through said slide slot in said mounting plate, said back-supporting strut unit further including a stop member abutting against said front side surface of said mounting plate and connected fixedly to said guiding projection unit to prevent removal of said connecting member from said mounting plate while permitting movement of said connecting member on said mounting plate.

3. The adjustable support frame as claimed in claim 2 , wherein said guiding projection unit includes two parallel ribs fixed on said front side surface of said connecting member and spaced apart from each other, said stop member being connected threadedly to said connecting member.

4. The adjustable support frame as claimed in claim 2 , wherein said stop member is formed with a dovetail groove, said second engaging member being received slidably within said dovetail groove.

5. The adjustable support frame as claimed in claim 4 , wherein each of said first and second engaging members has a serrated edge, said serrated edges of said first and second engaging members engaging each other when said driving member is disposed at said locking position.

6. The adjustable support frame as claimed in claim 1 , wherein said second engaging member is movable on said mounting plate along a first direction, and said driving member is movable on said mounting plate along a second direction perpendicular to said first direction.

7. The adjustable support frame as claimed in claim 6 , wherein said driving member is formed with two guiding arms projecting forwardly therefrom and aligned with each other along said second direction, said guiding arms extending in a direction inclined relative to said first and second directions, said adjusting unit further including: a sliding plate movable on said mounting plate along said first direction and having two guide slots extending parallel to said guiding arms, said guiding arms being movable respectively within said guide slots to move said sliding plate on said mounting plate along said first direction when said driving member moves on said mounting plate along said second direction, said second engaging member being connected to said sliding plate to allow for synchronous movement therewith; and a spring unit for biasing said second engaging member to engage said first engaging member.

8. The adjustable support frame as claimed in claim 7 , wherein said mounting plate has opposite front and rear side surfaces, said front side surface of said mounting plate being formed with a surrounding wall along a periphery thereof, said surrounding wall having a notch, said driving member having a neck portion extending through said notch to guide said driving member to move on said mounting plate along said second direction, and an end plate connected fixedly to said neck portion and perpendicular to said mounting plate, said end plate being disposed outwardly of said mounting plate for manual operation.

9. The adjustable support frame as claimed in claim 8 , wherein said sliding plate is formed with a retaining slot extending along said second direction, said second engaging member being disposed between said sliding plate and said first engaging member and having an end formed with an insert arm extending perpendicularly therefrom and inserted into said retaining slot in said sliding plate to allow for synchronous movement of said second engaging member and said sliding plate.

10. The adjustable support frame as claimed in claim 7 , wherein said spring unit includes at least one compression spring for biasing said sliding plate toward said first engaging member.

11. The adjustable support frame as claimed in claim 1 , wherein said biasing unit includes a tension spring interconnecting said mounting plate and said driving member.

说明书

[0001]一种低可溶性蛋白质含量的天然橡胶乳液的生产方法

[0002]技术领域

[0003]本发明涉及辐射技术领域，具体涉及一种低可溶性蛋白质含量的天然橡胶乳液的生产方法。

[0004]背景技术

[0005]天然橡胶乳液是以顺式聚异戊二烯为主体，含十几种组分的乳状液体，只有硫化后的天然橡胶才有应用价值。辐射硫化技术，即在天然橡胶乳液中加入少量的敏化剂，通过钴-60伽玛射线或电子束辐照，使橡胶分子产生交联，其制品的理化性能与化学硫化制品的理化性能相当。辐射硫化的天然橡胶乳液可用于医用手套、指套、安全套、导管和气球等生产。使用医用乳胶手套等会产生过敏反应，而天然乳胶中的水溶性蛋白质是过敏反应的主要原因，为此应尽可能地降低天然乳胶中的蛋白质含量。另一方面，随着人类生活水平的提高，健康安全意识也日益增强，国际国内市场上对无水溶性蛋白或低水溶性蛋白天然乳胶制品(医用手套、自粘绷带等)需求也越来越大。

[0006]发明内容

[0007]本发明的目的在于，给出一种低可溶性蛋白质含量的天然橡胶乳液的生产方法，该橡胶乳液的可溶性蛋白质含量低，生产方法简单、容易实施、效果好。

[0008]本发明给出的低可溶性蛋白质含量的橡胶乳液，其可溶性蛋白质含量不大于50μg/g，因此，本发明的乳液制成的医用手套、指套、安全套、导管和气球等产品不会引起使用者的蛋白质过敏反应。

[0009]本发明给出的低可溶性蛋白质含量的天然橡胶乳液的生产方法为：

[0010]①在搅拌条件下，向干胶重量百分比含量为30％-60％的天然橡胶乳液中，按每百份干胶0.5-1.5份聚乙烯醇的比例加入聚乙烯醇溶液，所说的聚乙烯醇溶液重量百分比浓度为10％，

[0011]②用氨水将上述乳液稀释至干胶含量为25％-30％的乳液，所说的氨水重量百分比浓度为0.75％，

[0012]③用离心机对稀释后的乳液进行离心，

[0013]④将橡胶相和乳清相分离，收集上层橡胶相，即得到降低了可溶性蛋白质含量、干胶含量≥60％的天然橡胶乳液。

[0014]在天然橡胶乳液中，乳清相和橡胶相中均含有蛋白质，橡胶相中多数蛋白质吸附在橡胶粒子表面。实验表明，随着辐照剂量的增加，可抽取蛋白质在乳液乳清相中含量增加了，而在橡胶相中的含量却减少了；制膜浸滤后，胶膜中的可提取蛋白质显著减少。这表明，电离辐射可使乳液中某些非水溶性蛋白质降解为水溶性蛋白质，原吸附在橡胶粒子上的蛋白质降解后会迁移并溶入乳清中。另外，聚乙烯醇可改变蛋白质在橡胶相和乳清相中的分配，使更多的水溶性蛋白质从橡胶相迁移到乳清相，并可通过乳液离心和胶膜浸滤除去，残留在胶膜中(产品中)的水溶性蛋白质就相应降低。

[0015]本发明的方法可用于降低天然橡胶乳液中的水溶性蛋白质，也可用于经过辐射硫化的天然橡胶乳液中水溶性蛋白质，应用本发明的方法得到的辐射硫化橡胶乳液，可生产出安全健康的优质乳胶制品，与现有技术采用的氯化处理降低可溶性蛋白质的方法相比，不会产生影响环境的氯化废水，十分有利于医疗卫生和环保事业。本发明具有方法简单、容易实施、成本低、可有效地降低橡胶乳液中水溶性蛋白质的含量等优点。

[0016]附图说明

[0017]本发明有如下附图：

[0018]图1方法流程示意图

[0019]具体实施方式

[0020]以下结合附图，对本发明作进一步详细说明。

[0021]本发明给出的低可溶性蛋白质含量的天然橡胶乳液，其可溶性蛋白质含量不大于50μg/g，为了生产这种低可溶性蛋白质含量的橡胶乳液，本发明给出了一种方法，其流程如图1所示，本发明的生产方法具体操作为：在搅拌条件下，向30％-60％DRC(干胶含量)的乳液中，加入0.5-1.5Phr(相对于每一百份干胶的干配比)PVA(聚乙烯醇)溶液，即每百份干胶加入0.5-1.5份聚乙烯醇，例如，可加入浓度为8-12％的聚乙烯醇溶液，加入量0.5、1.0、1.5、2.0、2.5和3.0phrPVA都是可以选择的方案。PVA溶液的浓度过大或过小都不适宜，因为，配制PVA溶液时需水浴加热或直接加热，并需搅拌，PVA溶液浓度过大时，极易结块或糊焦，也容易使PVA溶解不彻底，溶液中存在小颗粒PVA的溶液在工艺中是不能使用的；PVA溶液浓度过小时，由于所含水分较多，在乳胶稀释时，就会限制作为分散剂和保存剂使用的氨水用量，所以，聚乙烯醇溶液最佳浓度为10％。操作时要充分搅拌，配料完毕后可继续搅拌混合，以使配料混合均匀。然后，用氨水，例如可以用0.75-1.0％的氨水，将上述乳液稀释至干胶含量为25％-30％的乳液，氨水是应用最广的保存剂，可保持系统为碱性，并具有分散作用和抑制酶、菌的作用，防止天然橡胶乳液变质腐败。由于氨水中的氨气极易挥发，浓度越高越易挥发，对环境造成不良影响；另一方面，国家标准规定，高氨离心浓缩天然橡胶乳液中氨含量需≥0.6％，所以，氨水的最佳浓度为0.75％，用作橡胶乳液稀释用的分散剂和保存剂较为合适。稀释后放置一段时间，例如可放置2小时或2小时以上，放置的目的是使聚乙烯醇分子与乳液中蛋白质分子有充分的时间相互作用，以便迁移和解析蛋白质分子。然后，用离心机对稀释后的乳液进行离心，离心机最好选用乳胶浓缩专用工业离心机，例如，南京绿洲机器厂生产的7200转/分的工业离心机，将橡胶相和乳清相分离，收集上层橡胶相，即得到降低了可溶性蛋白质含量的天然橡胶乳液。

[0022]以下是本发明的一个实施例：

[0023]称取约25kg60％DRC的天然橡胶乳液，在搅拌条件下，加入浓度10％的PVA溶液1Phr或2Phr，相应的重量为1.5kg或3.0kg，随后加入0.75％的氨水23.5kg或22kg，将上述混合液稀释到30％DRC乳液，放置2小时后，用工业离心机(乳胶浓缩专用，7200转/分)离心，并自动分离橡胶相和乳清相；收集上层橡胶相，由于离心机的作用，其浓缩乳液浓度≥60％DRC，乳液离心可去除乳清相中大部分的蛋白质，包括水溶性蛋白质。

[0024]以下是本发明的另一个实施例：

[0025]称取约25kg50％DRC的经过辐射交联的天然橡胶乳液，在搅拌条件下，加入浓度10％的PVA溶液1Phr或2Phr，相应的重量为1.25kg或2.5kg，随后加入0.75％的氨水23.75kg或22.5kg，将上述混合液稀释到25％DRC橡胶乳液，放置2小时后，用工业离心机(乳胶浓缩专用，7200转/分)离心，并自动分离橡胶相和乳清相；收集上层橡胶相，由于离心机的作用，其浓缩乳液浓度≥60％DRC，乳液离心可去除乳清相中大部分的蛋白质，包括水溶性蛋白质。

[0026]以下是本发明的再一个实施例：

[0027]称取约25kg30％DRC的经过辐射交联的天然橡胶乳液，在搅拌条件下，加入浓度10％的PVA溶液1Phr或2Phr，相应的重量为0.75kg或1.5kg，随后加入0.75％的氨水4.25kg或3.5kg，将上述混合液稀释到25％DRC橡胶乳液，放置2小时后，用工业离心机(乳胶浓缩专用，7200转/分)离心，并自动分离橡胶相和乳清相；收集上层橡胶相，由于离心机的作用，其浓缩乳液浓度≥60％DRC，乳液离心可去除乳清相中大部分的蛋白质，包括水溶性蛋白质。

[0028]由于加入的PVA为可溶性高极性的物质，它可改变蛋白质在橡胶相和乳清相中的分配，PVA通过解析部分原吸附在橡胶粒子上的蛋白质，使其从橡胶相迁移到乳清相，通过离心而除去，这样乳液中水溶性蛋白质的含量就大大降低。经过离心处理后，制成的胶膜中残留的水溶性蛋白质含量从原始的400-600μg/g降低到不大于50μg/g的水平。美国FDA(食品及药品管理局)要求每只医用手套的水溶性蛋白质含量不得大于1200μg，通常每只医用手套的重量为10g左右，那么采用上述离心处理后制成的每只手套中水溶性蛋白质的含量约为500g，明显低于FDA的要求。可见，本发明具有很高的应用价值。

[0029]本发明的研究结果显示，PVA浓度效应并不显著，在所选浓度范围内(0.5-3.0phr)均有相似的效应。考虑成本因素，在实际应用时可选择最佳值2phr。

[0030]本发明的研究结果还显示，对胶膜进行浸滤，也可抽提出部分残留的水溶性蛋白质，通过离心和浸滤两者的结合，可以获得极低水溶性蛋白质含量的制品。在浸渍制品(手套、避孕套、胶管、婴儿奶嘴等)生产线上均有浸滤工艺，不需更改原有生产工艺，可节省生产厂家的开支。

同族专利

暂无同族专利

专

一种抗菌丹参酮提取物、其制备方法、用途及其产品

KR08737882B2

发明人

钟忠

受让人

BOZHONG SHENGJING MEDICAL TECH

申请人

Byung-lyul Park, Gil-heyun Choi, Pil-kyu Kang, Dae-lok Bae, Dong-kak Lee

申请号

102477

申请日

1992-09-18

公开(公告)号

KR08737882B2

公开(公告)日

2007-09-26

IPC分类号

B21D039/20A44B019/46B21D039/08A44B019/42A41H037/06B21D053/54

CPC分类号

优先权号

3923077

优先权日

1977-09-19

摘要

USE -For TV, videophone, etc.

ADVANTAGE -Is easy to manufacture, with simplified structure and generates strongly collimated light.

权利要求

4. The adjustable support frame as claimed in claim 2 , wherein said stop member is formed with a dovetail groove, said second engaging member being received slidably within said dovetail groove.

10. The adjustable support frame as claimed in claim 7 , wherein said spring unit includes at least one compression spring for biasing said sliding plate toward said first engaging member.

11. The adjustable support frame as claimed in claim 1 , wherein said biasing unit includes a tension spring interconnecting said mounting plate and said driving member.

说明书

[0001]一种低可溶性蛋白质含量的天然橡胶乳液的生产方法

[0002]技术领域

[0003]本发明涉及辐射技术领域，具体涉及一种低可溶性蛋白质含量的天然橡胶乳液的生产方法。

[0004]背景技术

[0006]发明内容

[0009]本发明给出的低可溶性蛋白质含量的天然橡胶乳液的生产方法为：

[0011]②用氨水将上述乳液稀释至干胶含量为25％-30％的乳液，所说的氨水重量百分比浓度为0.75％，

[0012]③用离心机对稀释后的乳液进行离心，

[0013]④将橡胶相和乳清相分离，收集上层橡胶相，即得到降低了可溶性蛋白质含量、干胶含量≥60％的天然橡胶乳液。

[0016]附图说明

[0017]本发明有如下附图：

[0018]图1方法流程示意图

[0019]具体实施方式

[0020]以下结合附图，对本发明作进一步详细说明。

[0022]以下是本发明的一个实施例：

[0024]以下是本发明的另一个实施例：

[0026]以下是本发明的再一个实施例：

[0029]本发明的研究结果显示，PVA浓度效应并不显著，在所选浓度范围内(0.5-3.0phr)均有相似的效应。考虑成本因素，在实际应用时可选择最佳值2phr。

同族专利

暂无同族专利