INTRODUCTION:Myofasciitis, a prevalent cause of musculoskeletal pain, is associated with thoracolumbar fascial changes. Acupuncture is effective for pain relief, but its role in fascial repair remains unclear. This study examined the effects of electroacupuncture (EA) at BL23 (Shenshu) and BL40 (Weizhong) on fascial tissue repair in a rat model of thoracolumbar fasciitis (TLF). METHODS:The study involved 42 six-week-old Sprague-Dawley rats divided into control (n = 15) and modeling (n = 27) groups. TLF was induced by injecting complete Freund's adjuvant into the thoracolumbar fascia. Three rats in the control and modeling groups were used for model validation. The remaining 24 modeled rats were split into model and EA groups (n = 12 each). EA was administered at BL23 and BL40 to rats in the EA group for 20 min daily for 9 days. Assessments included skin pain sensitivity, musculoskeletal ultrasound, histological evaluation of fascial thickness, and measurement of inflammatory markers and fibroblast activity. RESULTS:EA-treated rats showed significant improvements, including reduced mechanical pain sensitivity, decreased fascial thickness and lower expression of pro-inflammatory markers (tumor necrosis factor-α, interleukin 1β) and fibroblast activity markers (proliferating cell nuclear antigen, α-smooth muscle actin, and vimentin). There was also a favorable balance in extracellular matrix components (increased type I/III collagen and matrix metalloproteinase (MMP)-1/tissue inhibitor of MMP (TIMP)-1 ratios), which was linked to reduced activity of the transforming growth factor (TGF)-β1/suppressor of mother against decapentaplegic (Smad)2 pathway. CONCLUSION:EA at BL23 and BL40 reduces inflammation, inhibits fibroblast proliferation and activation, and promotes fascial repair, likely via modulation of the TGF-β1/Smad2 pathway. These findings support the therapeutic potential of EA for the treatment of myofasciitis, potentially aiding in chronic musculoskeletal pain management and fascial tissue repair.

Objective Electroacupuncture has demonstrated beneficial effects in post-stroke motor dysfunction, yet the molecular mechanisms underlying its therapeutic efficacy remain incompletely understood. This study aims to investigate whether electroacupuncture promotes post-stroke motor function recovery by modulating the interaction between miR-124-3p and the NRG1/ErbB4 signaling pathway, specifically exploring whether miR-124-3p directly targets NRG1 to regulate neural plasticity in a focal cerebral ischemia rat model. Methods The ischemic stroke model was established by middle cerebral artery occlusion/reperfusion (MCAO/R) in adult rats. These rats were randomly divided into sham, model, electroacupuncture and model plus miR-124-3p inhibitor groups. The model group, electroacupuncture group and model plus miR-124-3p inhibitor group received EA intervention 24 h after modelling for 7 consecutive days. Behavioural function was assessed by Zea Longa score and mechanical pain rating. Hippocampal damage was detected by HE staining and neuronal apoptosis was observed by TUNEL staining. IL-1β and IL-18 levels were measured by ELISA. PCR and Western blotting were used to detect the expression of miR-124-3p and inflammatory pathway proteins. The interaction between miR-124-3p and TLR4 was verified by dual-luciferase reporter assay. Results Electroacupuncture improved motor function in rat model of MCAO/R, as evidenced by improved Zea Longa scores and decreased mechanical withdrawal thresholds. Electroacupuncture significantly attenuated neuronal damage and also inhibited the inflammatory response by decreasing IL-18 and IL-1β levels (P < 0.001). Notably, electroacupuncture upregulated miR-124-3p expression (P < 0.0001) and activated the NRG1/ErbB4 signaling pathway in the hippocampus. When miR-124-3p was inhibited, NRG1 protein expression decreased while GABA expression tended to increase. Dual-luciferase reporter assays confirmed that miR-124-3p directly targets the 3’UTR of NRG1 mRNA and regulates its expression at the translational level. These findings suggest that electroacupuncture may alleviate neuronal and axonal damage by modulating miR-124-3p/NRG1/ErbB4 signalling and regulating GABA release. Conclusion Electroacupuncture can ameliorate motor dysfunction induced after brain I/R injury by targeting and modulating the NRG1-ErbB4 signaling pathway via miR-124-3p. These data are expected to provide new insights into the mechanisms of electroacupuncture for the prevention of potential targets for the recovery of motor dysfunction after stroke. ### Competing Interest Statement The authors have declared no competing interest. the Joint Fund Project of Fujian Provincial Natural Science Foundation in 202, 2022J011019 the 2022 Fujian Provincial Health and Health Youth Backbone Training Project, 2022GA009 the 2024 Fujian Provincial Science and Technology Innovation Joint Fund Project, 2024Y907 the 2022 Fujian Medical University Start-up Fund General Project, 2022QH1287

BackgroundAcupuncture is widely used for Lower Limb Motor Dysfunction Following Stroke (LLMD) in China, though its effectiveness remains unclear. This meta-analysis aims to evaluate the effectiveness of acupuncture for LLMD.MethodsWe searched eight databases, including PubMed, Embase, Web of Science, Cochrane Library, China National Knowledge Infrastructure, Wanfang, VIP, and CBM, up to December 2023. Randomized controlled trials on acupuncture therapy for LLMD after stroke were included in this study. Outcome measures included motor function, balance function, walking ability, and daily living activities. Two researchers conducted independent literature screening, data extraction, and quality assessment in accordance with Cochrane Collaboration network's standards. Review Manager 5.3 and Stata 17.0 were used in data analysis. Results were presented as mean difference (MD) or standardized mean difference (SMD) with 95% confidence interval (95% CI).ResultsTwelve studies involving 1318 patients, most of which showed low or unclear risk of bias, were included in this review. Meta-analysis results indicate that compared with conventional treatment, acupuncture intervention can improve scores in Fugl-Meyer Assessment for lower scale (SMD = -0.48, 95% CI [-0.92, -0.04], Z = 2.16, P = .03), Berg Balance Scale (SMD = -0.86, 95%CI [-1.65, -0.07], Z = 2.14, P = .03), Functional Ambulation Category scale (SMD = -0.74, 95%CI [-2.33, 0.84], Z = 0.92, P = .36), and Modified Barthel Index Scale (SMD = 0.27, 95%CI [-0.30, 0.84], Z = 0.94, P = .35).ConclusionThe results of this study suggest that acupuncture combined rehabilitation training may be more effective than conventional rehabilitation alone in improving LLMD, balance function, walking ability, and daily living activities after stroke. Despite limitations due to the low quality of the included studies and methodological constraints, acupuncture combined with rehabilitation training may serve as an effective approach for the treatment of LLMD poststroke.

AbstractsBackgroundKnee osteoarthritis (KOA) is a common degenerative joint disease that severely affects patients’ quality of life. Joint-mobilization technique reportedly improves joint pain, limited mobility, and dysfunction significantly. This meta-analysis aimed to systematically assess the clinical efficacy of joint-mobilization technique treatment on the level of knee pain, function, and mobility in patients with KOA. We also aimed to provide evidence-based medical data for the clinical management of KOA.MethodsWe searched four English databases (PubMed, Web of Science, Embase, and Cochrane) and three Chinese databases (China Biomedical Literature Database, CNKI, VIP, and Wanfang). The search date was from the date of inception to February 1, 2024 for each database. Randomized controlled trials investigating the efficacy of joint release in KOA were identified. Meta-analysis was performed using RevMan 5.4 and Stata 17.0.ResultsA total of 8 studies involving 432 patients with KOA were included. Our meta-analysis showed that compared with the control group, the experimental group showed a significant improvement in knee pain level (SMD=-1.69, 95% CI [-1.74, -0.82] Z=3.96 P<0.0001), WOMAC scale (SMD=-0.74 95% CI [-1.39, -0.10] Z= 2.25 P=0.02) were significantly improved. However, they were not superior to controls in knee flexion (SMD=2.3 95% CI [0.98, 3.62] Z=3.41 P=0.00006) and extension mobility (SMD=1.79, 95% CI [1.38, 2.20], Z=8.54,P<0.00001).ConclusionJoint-mobilization technique has some advantages in improving the degree of knee pain and dysfunction in patients with KOA, but it is not better than the control group in improving knee mobility. This study provides theoretical support for the promotion of joint-mobilization technique in KOA treatment.

AbstractBackgroundAcupuncture is widely used for Lower Limb Motor Dysfunction Following Stroke (LLMD) in China but its effect is unclear. We aim to evaluate the effect of acupuncture for LLMD.MethodsWe searched eight databases, including PubMed, Embase, Web of Science, Cochrane Library, China National Knowledge Infrastructure, Wanfang, VIP, and CBM, up to December 2023. Randomized controlled trials on acupuncture therapy for LLMD after stroke were enrolled in this study. Outcome measures comprised motor function, balance function, walking ability, and daily living activities. Two researchers conducted independent literature screening, data extraction, and quality assessment in accordance with Cochrane Collaboration network’s standards. Review Manager 5.3 and Stata 17.0 were used in data analysis. Results were presented as mean difference (MD) or standardized mean difference (SMD) with 95% confidence interval (95% CI).ResultsTwelve studies involving 1318 patients, most of which showed low or unclear risk of bias, were included in this review. Meta-analysis results indicate that compared with conventional treatment, acupuncture intervention can improve scores in Fugl–Meyer Assessment for lower scale (SMD=0.41, 95% CI (−0.92, –0.04), Z=2.16, P =.03), Berg Balance Scale (SMD=-0.86, 95%CI (−1.65, –0.07), Z=2.14, P=.03), Functional Ambulation Category scale (SMD=-0.74, 95%CI (−2.33, 0.84), Z=0.92, P=.36), and Modified Barthel Index Scale (SMD=0.27, 95%CI (−0.30, 0.84), Z=0.94, P=.35).ConclusionThe results of this study suggest that acupuncture combined rehabilitation training may be more effective than pure treatment in improving LLMD, balance function, walking ability, and daily living activities after stroke. Despite limitations due to the low quality of the included studies and methodological constraints, acupuncture combined rehabilitation training may serve as an effective approach for the treatment of LLMD poststroke.

目的:探讨穴位埋线治疗对单纯性肥胖患者脂质代谢和内分泌激素水平的影响.方法:招募60位单纯性肥胖患者,并采用SPSS22.0生成随机数字,将其随机分为穴位埋线组和对照组,各30例.对照组采用健康生活管理方法,穴位埋线组则在此基础上加入了穴位埋线治疗.疗效评估指标包括体质指数(BMI)、腰围(WC)、腰臀比(WHR)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、促甲状腺素(TSH)、瘦素(Leptin)和胰岛素(INS)等指标的变化情况.结果:埋线组和对照组的BMI、WC、WHR均有下降趋势,并且穴位埋线组在这些指标上的表现优于对照组(P＜0.05).此外,穴位埋线组的TC、TG、LDL-C、TSH、Leptin和INS水平均明显下降,而HDL-C水平则明显提高(P＜0.05).结论:穴位埋线能够有效降低单纯性肥胖患者的体重、腰围和腰臀比,改善瘦素和胰岛素抵抗,改善脂质代谢水平.

Objective:To observe any effect of tendon manipulation on the joint pain, joint motion and gait of persons with knee osteoarthritis (KOA).Methods:Sixty-one KOA patients were randomly divided into an observation group ( n=31) and a control group ( n=30). Both groups received ultrasonic physiotherapy and exercise trai-ning (including quadriceps femoris training and heel raising training), while the observation group was additionally provided with daily tendon manipulation, five times a week for 3 weeks. Before and after the treatment, knee pain (using a visual analog scale (VAS)), motor function (using the Western Ontario and McMaster University (WOMAC) osteoarthritis index scale), step length, gait speed and the double support phase ratio were evaluated in both groups using three-dimensional gait analysis equipment. Results:After the treatment the average VAS scores, as well as the joint pain, stiffness and dysfunction and the total WOMAC scores of both groups had decreased significantly. There was significant improvement in the average stride length, walking speed and the proportion of double support phase among the observation group, and the latter two measurements had also improved significantly in the control group. After the intervention, the average pain, WOMAC scores and gait descriptors of the observation group were significantly superior to the control group′s results.Conclusion:Tendon manipulation can usefully supplement routine rehabilitation in the treatment of KOA, improving walking efficiency and thus life quality.

Abstract Background: Postoperative cognitive dysfunction (POCD) is the progressive deterioration of cognitive function after surgery. The mechanism underlying the development of POCD is unclear. Previous studies have suggested that neuroinflammation is a major contributor to the development of POCD. The purpose of this study was to observe the effects of preoperative pain on inflammatory factors and neuronal apoptosis in the hippocampus. Methods: Cognitive function was evaluated by the Morris water maze (MWM), and the expression levels of pro-inflammatory cytokines (IL-6, IL-1β, and TNF-α) were measured on the 1st, 3rd and 7th days after surgery. The levels of Ach, cAMP, PKA, and GABAA in the hippocampus were measured at the same time points. Results: Our results showed that the rats that experienced preoperative pain exhibited impaired learning and memory after surgery (P< 0.001). Moreover, rats in the preoperative pain+surgery group exhibited increased neuronal apoptosis compared to that of rats in the surgery group. On the 1st, 3rd and 7th days after surgery, the expression of IL-1β, IL-6 and TNF-α in the pain+surgery group was increased compared to that in the surgery group (P<0.001). Furthermore, the expression of key proteins, including ACh, cAMP, PKA and GABAA, was decreased in the pain+ surgery group compared to the surgery group. Conclusions: Preoperative pain may be a key risk factor for the development of POCD by inhibiting the cholinergic anti-inflammatory pathway (ACh-cAMP-PKA signalling pathway) and decreasing the expression of GABAA in the CNS.

目的 研究经络辨证针刺联合八段锦治疗肩周炎患者肩活动度的临床疗效.方法 将70例肩周炎患者随机分为针刺组和联合组,每组各35例,针刺组采用经络辨证取穴针灸治疗,联合组在针刺组的基础上配合八段锦功法锻炼,共治疗4周.观察2组患者视觉模拟量表(VAS)评分和肩关节主动活动度(ROM)的变化,并评价临床疗效.结果 2组治疗后VAS评分均较治疗前明显降低(P<0.001),而2组治疗后VAS评分比较差异无统计学意义(P>0.05).2组治疗后肩关节各方向活动度均较治疗前明显改善(P<0.001);治疗后联合组患者在前屈、外展、内旋、外旋和内收5个方向的活动度均大于针刺组(P<0.05),在后伸方向2组之间的差异无统计学意义(P>0.05).针刺组和联合组患者的愈显(治愈+显效)率分别为51.43％和85.71％,联合组明显高于针刺组(P<0.001);针刺组和联合组的总有效(治愈+显效+有效)率分别为91.43％和94.28％,差异无统计学意义(P>0.05).结论 2组治疗方法均能减轻患者疼痛症状,增加关节活动度,而联合组在增加关节活动度方面具有更好的效果.

Review question / Objective: To evaluate the efficacy of Manual Acupuncture in the treatment of Migraine Without Aura.Eligibility criteria: We included trials with individualized strategies when the average number of treatments was at least five.Additionally, to assure the clinical efficacy of acupuncture treatments, the acupuncturist administering the treatments in the study should have a relevant acupuncture qualification or practice qualification.In addition, the acupuncturist should have prior clinical experience.

Background: Chronic low back pain (CLBP) is 1 of the common clinical diseases, and many treatment methods can only improve the symptoms of pain in the short term. Traditional Chinese sports - Baduanjin has been proven to have a positive effect on chronic low back pain. However, the quality of the research is low, the sample size is small, and safety observations are lacking. We describe the protocol of a randomized controlled trial to study the efficacy and safety of Baduanjin chronic low back pain. Methods: This randomized, controlled, evaluator-blind, two-arm, parallel clinical trial will include 90 outpatients with chronic low back pain recruited from the First Hospital of Nanping City, Fujian Province. The patients were randomly assigned to the intervention group (Baduanjin exercise training) and the control group (not receiving any special exercise training) at a ratio of 1:1. Patients in the intervention group will receive Baduanjin exercise training 3 times a week for 24 weeks. The 2 groups received a 4- week follow-up observation at 24 weeks. The main result from the intervention before intervention to 24 weeks later, and the follow-up of 4 changes the visual analog scale score at weeks, and by independent t are tested groups. It will also review the Pain-related disability index, The Quebec Back Pain Disability Scale, Health-related quality of life, Roland Morris (Roland Morris) Disability Questionnaire, Overall Perceived Effect (OPE) and safety Compare. Cost data for cost-benefit and cost-benefit analysis will be collected. Discussion: This will be the first study to compare the effectiveness and safety of Baduanjin for patients with chronic low back pain. The results may help healthcare professionals make clinical decisions and may reduce the cost of treatment for this disease.

Abstract Background: Chronic low back pain (CLBP) is 1 of the common clinical diseases, and many treatment methods can only improve the symptoms of pain in the short term. Traditional Chinese sports - Baduanjin has been proven to have a positive effect on chronic low back pain. However, the quality of the research is low, the sample size is small, and safety observations are lacking. We describe the protocol of a randomized controlled trial to study the efficacy and safety of Baduanjin chronic low back pain. Methods: This randomized, controlled, evaluator-blind, two-arm, parallel clinical trial will include 90 outpatients with chronic low back pain recruited from the First Hospital of Nanping City, Fujian Province. The patients were randomly assigned to the intervention group (Baduanjin exercise training) and the control group (not receiving any special exercise training) at a ratio of 1:1. Patients in the intervention group will receive Baduanjin exercise training 3 times a week for 24 weeks. The 2 groups received a 4- week follow-up observation at 24 weeks. The main result from the intervention before intervention to 24 weeks later, and the follow-up of 4 changes the visual analog scale score at weeks, and by independent t are tested groups. It will also review the Pain-related disability index, The Quebec Back Pain Disability Scale, Health-related quality of life, Roland Morris (Roland Morris) Disability Questionnaire, Overall Perceived Effect (OPE) and safety Compare. Cost data for cost-benefit and cost-benefit analysis will be collected. Discussion: This will be the first study to compare the effectiveness and safety of Baduanjin for patients with chronic low back pain. The results may help healthcare professionals make clinical decisions and may reduce the cost of treatment for this disease. Trial registration: ChiCTR2000033908

目的:探讨关节松动术治疗运动员急性踝关节扭伤的疗效,进一步分析其作用机理.方法:收集2018年1月至2019年6月就诊于福建体育科学研究所康复中心的急性踝关节扭伤患者60例,将其随机分为实验组(关节松动术组)30例,对照组(非关节松动术组)30例,实验组采取关节松动术结合冷疗与针刺;对照组冷疗与针刺.分别在治疗前和治疗5天后进行两组患者踝关节症状体征评定以及Prokin254测试,并在治疗5天后进行疗效评定.结果:两组患者治疗前各项指标差异无统计学意义(P>0.05),具有可比性;治疗后组内比较,两组患者各项指标的改善均比治疗前有非常显著差异(P<0.01);治疗后组间比较,实验组症状体征总分、平均轨迹误差(ATE)、负重感觉缺失度(AFV)、稳定指数(SI)改善均比对照组有显著差异(P<0.05),但两组身体压力中心轨迹运动的总面积(S)、身体压力中心轨迹运动的总长度(L)差异无统计学意义(P>0.05);实验组总治愈率高于对照组,有显著差异(P<0.05).结论:关节松动术结合冷疗与针刺对于运动员急性踝关节扭伤的症状缓解优于单纯冷疗与针刺,并且可以有效改善踝关节本体感觉和稳定性,提高总体治愈率.

目的 观察中药熏洗配合静态进展性牵伸治疗上肢骨折术后早期肘关节功能障碍的临床疗效.方法 选取78例上肢骨折术后早期肘关节功能障碍患者,按随机数字表分为治疗组和对照组,每组39例.两组均采用常规康复治疗,即关节松动术与肌力训练,治疗组加中药熏洗配合静态进展性牵伸治疗,每日1次,共治疗4周.于治疗前后分别记录患者改良HSS肘关节功能评分(HSS),采用改良Barthel指数(MBI)评价患者日常生活活动能力(ADL),测量患者肘关节活动度.结果 治疗组5例、对照组3例未完成全部康复治疗疗程,但已超过2周,计入疗效评价.与本组治疗前比较,治疗4周后,两组患者HSS、MBI评分以及肘关节活动度均升高(P＜0.05),且治疗组HSS及肘关节活动度优于对照组(P＜0.05).两组治疗期间均未发生明显不良反应.结论 在常规康复治疗的基础上,中药熏洗配合静态进展性牵伸能有效改善上肢骨折术后早期患者肘关节运动功能与关节活动度,提高生活自理能力.

Background Perioperative neurocognitive disorder (PND) is the progressive deterioration of cognitive function after surgery. The purpose of this study was to observe the effect of preoperative pain on inflammatory factors and neuronal apoptosis in the hippocampus of rats. Methods 36 adult male Sprague-Dawley rats were randomly divided into 4 groups: the control group, the pain group, the pain+operation group, and the operation group. 6 days before the surgery, the rats received cognitive training, and the cognitive evaluation was carried out on the1, 3 and 7th days after the surgery. The rats were killed on the first, third and seventh days after the surgery (n = 3 rats/day). The cognitive function of rats was evaluated by the Morris Water Maze (MWM), and the expression levels of the pro-inflammatory cytokines interleukin 6(IL-6), Interleukin 1β(IL-1β)and Tumor Necrosis Factor-α(TNF-α), Acetylcholine(Ach)and Cyclic Adenosine monophosphate(cAMP), protein kinase A(PKA)and gamma-aminobutyric acid type A receptors(GABAA) in the hippocampus were measured on the 1st, 3rd and 7th days after the operation. Results Our results showed that the pain model rats exhibited impaired behavior on the first day (P< 0.001), and this lasted until the 7th day after the operation (P≤0.002 and P≤0. 001, respectively). Preoperative pain model rats showed a higher level of apoptosis than that shown by the simple operation rats. On the 1st, 3rd and 7th days after the operation, the protein content of IL-1β, IL-6 and TNF-α in the pain operation group was increased compared to that in the simple operation group (P<0.001). ACh, cAMP, PKA and GABAA expression in the hippocampus was decreased after operation in the preoperative pain model rats. Conclusion Preoperative pain is a key risk factor for the development of PND. The ACh-PKA-GABAA signaling pathway plays a key role in the acetylcholine pathway.

Objective To investigate the effect of needle-warmed moxibustion on chondrocyte apoptosis and the lubricin protein content of osteoarthritic knees.Methods Forty New Zealand white rabbits were randomly divided into a sham operation group,a model group,a Western medicine group and a needle-warmed moxibustion group,each of 10.Knee osteoarthritis was induced in all except the sham operation group by injecting an aqueous solution of papain into the outer edge of one patellar tendon at the inferior pole of the patella.In the sham operation group the injection needle was only inserted and withdrawn.The needle-warmed moxibustion group had needle-warmed moxibustion applied to the internal and external DUBI acupoints 14 days after the modelling in 2 courses of treatment.The Western medicine group was given diclofenac sodium (15 mg/kg body weight) by gavage on the same schedule.The sham operation group and the model group were fed normally without special treatment.At the end of the treatment,knee cartilage tissue was resected from each group and the number of chondrocytes and the expression of lubricin in the articular cartilage cells were compared.Results Compared with the model group and the Western medicine group,the number of chondrocytes in the moxibustion group was significantly greater and the cells were arranged more neatly.TUNEL staining showed that the apoptosis rate of chondrocytes in the moxibustion group was significantly lower.A reverse transcription polymerase chain reaction showed that the expression of lubricin mRNA in the moxibustion group had increased significantly.Western blotting showed that the expression of lubricin protein was also significantly enhanced in the moxibustion group.Conclusions Needle-warmed moxibustion has a positive therapeutic effect on knee osteoarthritis,at least in rabbits.It can inhibit the apoptosis of knee chondrocytes and promote the secretion of lubricin.

目的 探讨双氯芬酸二乙胺乳胶剂作为耦合剂,体外冲击波(ESW)治疗肩袖损伤患者即时疼痛的疗效.方法 选取符合研究标准的64例肩袖损伤患者,采用随机数字表随机分为治疗组和对照组,每组32例,治疗组采用ESW联合双氯芬酸二乙胺乳胶剂耦合剂治疗,对照组采用ESW配合医用超声耦合剂治疗,ESW能量1.2～2.0 Bar,频率10.0 Hz,每次治疗冲击次数6000次,每次治疗时间10 min.每5日治疗1次,共治疗4次.分别观察2组患者在首次治疗前及第4次治疗结束后第5天(治疗后)的视觉模拟量表(VAS)评分,并于每次治疗过程中的第0(冲击波探头接触皮肤治疗开始)、3、6、9分钟以及每次治疗结束后第0(冲击波探头离开皮肤治疗结束)、5、10、15、20分钟时评定2组患者的即时VAS评分.结果 治疗后,2组患者的VAS评分[治疗组(1.22±0.71)分,对照组(1.28±0.85)]明显低于组内治疗前[治疗组(5.25±1.24)分,对照组(5.09±1.09分],且差异均有统计学意义(P<0.01);但2组患者治疗前和治疗后的VAS评分组间比较,差异均无统计学意义(P>0.05).在第1次治疗过程中的第6分钟和第9分钟时、第2次治疗过程中的第9分钟以及第1次治疗结束后的第5、10、15、20分钟时、第2次治疗结束后的第10、15、20分钟、第3次治疗结束后的第15分钟和第20分钟、第4次治疗结束后的第20分钟时,治疗组患者的VAS评分均明显低于同时间点对照组,组间差异有统计学意义(P<0.05).结论 双氯芬酸二乙胺乳胶剂耦合下,更能有效缓解冲击波治疗过程中产生的疼痛.

Objective:To observe the effect of new Bobath technology combined with intelligent motion feedback training on hand function of stroke patients with hemiplegia.Methods:A total of 68 stroke patients with hemiplegia were randomly divided into control group and treatment group, with 34 cases in each group. The control group was treated with routine rehabilitation therapy and occupational therapy, while the treatment group was treated with new Bobath technique and ntelligent motion feedback training on the basis of the control group.FMA-UE score of wrist motor function, MBI score of daily living ability and maximum activity of wrist joint dorsal extension on hemiplegic side were compared between the two groups.Results:After treatment for two, four and six weeks, the FMA-UE, MBI score and wrist dorsal extension maximum activity of the two groups improved significantly than those of treatment before, with statistically significant differences (P<0.05); After treatment for four and six weeks, the FMA-UE score and wrist dorsal extension maximum activity of the treatment group were significantly better than those of the control group, with statistically significant differences (P<0.05);after treatment for six weeks, MBI score of the treatment group was significantly better than that of the control group, with statistically significant differences (P<0.05).Conclusion:New Bobath technology combined with ntelligent motion feedback training can effectively improve hand function and self-care ability of stroke patients with hemiplegia.

目的:研究一个预测模型,用于福州地区周围性面瘫高危人群的筛查,并量化危险因素与周围性面瘫的关系.方法:选取福建省立医院针灸科就诊的周围性面瘫患者168例为病例组,另选择同时期192例健康体检者作为对照组,获得研究对象的知情同意后收集资料.对病例组和对照组之间各项危险因素的差异进行分析,并对其进行logistic回归分析与因子分析.结果:危险因素中受寒史、病毒感染史、疲劳、焦虑、压力等的差异均有统计学意义(P＜0.05).多因素非条件logistic模型结果显示,受寒史、病毒感染史、疲劳、焦虑、压力对跌倒的预测最有意义,并做出预测模型.通过因子分析,受寒史提取为面瘫危险因素的主成分.结论:该模型可用于福州地区周围性面瘫高危人群的筛查,量化高危因素与周围性面瘫的关系,为周围性面瘫预防提供数据.

Objective: To observe the efficacy of "tongue three needles" combined with neuromuscular electrical stimulation for dysphagia after stroke. Methods:87 cases of patients were randomly divided into electrical stimulation group (43 cases) and acupuncture group (44 cases). The elec-trical stimulation group treated by neuromuscular electrical stimulation, while acupuncutre group by"tongue three needles"on the basis of neuromus-cular electrical stimulation. Results:After treatment, the improvement of water swallow test score was better than that of before treatment (P<0.05), and the score improvement of acupuncture group was better than electrical stimulation group (P<0.05); the overall response rate of acupuncture group was significantly high than that of electrical stimulation group (P<0.05). Conclusion:The treatment of"tongue three needles"combined with neuromuscular electrical stimulation can significantly improve the swallowing function of stroke patients.