深在性囊性胃炎(gastritis cystica profunda,GCP)是一种临床罕见的胃黏膜下病变,因无特异性的临床症状和内镜下表现,术前明确诊断仍存在困难.既往观点多认为 GCP 是一种良性病变,但近年来与胃癌伴发的 GCP 病例报道逐渐增多,提示 GCP 可能与胃癌的发生发展存在一定相关性.本文从 GCP 的病因及发病机制、临床表现、诊断、治疗及预后,特别是与胃癌的关系等方面进行了综述,总结了 GCP 目前的临床研究进展,以加深临床医师对这一罕见病的理解,为 GCP 诊疗提供理论依据.
深在性囊性胃炎(GCP)是一种罕见的以胃黏膜下腺体囊性增生为特征的胃部病变,常见病变部位为胃窦和胃体,累及胃体、胃窦多部位的GCP病例罕有报道。本文报道1例胃体、胃窦部多发GCP且伴有高级别上皮内瘤变患者的诊治经过,以期提高临床医师对该病的认识。
特发性嗜酸性粒细胞增多症(idiopathic hypergranulocytosis,IHES)是一组发病原因不明的疾病,临床工作中不常见,它累及多个器官系统,激素是一线治疗药物.现报道1例我院收治的IHES的诊疗经过,供临床参考.
非甾体类抗炎药(NSAIDs)为抗炎、解热镇痛、抑制血小板聚集的有效药物,被广泛应用于临床.但其不良反应众多,应用不恰当则弊大于利,严重危害患者生命健康.其最主要的不良反应为胃肠道(GI)损伤.近年来,学者们就NSAIDs对胃黏膜损伤的研究较多,而在一定程度上忽略了其对肠道黏膜损伤的影响,本文就NSAIDs对肠道黏膜损伤的发生机制、临床表现、检查异常及防治等进行综述.
Objective:To analyze the clinical characteristics of ischemic colitis(IC) and further improve the diagnosis and treatment of the disease.Methods:The clinical manifestations, risk factors, colonoscopy and abdominal CT examination results of 35 patients with IC confirmed from January 2014 to December 2018 in the Second Hospital of Jilin University were retrospectively analyzed, and their clinical characteristics were summarized.Results:The sudden manifestation of abdominal pain and blood in 31 cases of the 35 patients were the main manifestations.Ten patients who underwent abdominal CT scan showed a thickened bowel wall with a thickness of (7.92±1.41)mm.The CT value of the thickened bowel wall decreased significantly to (21.20±2.27)Hu.In 35 cases of colonoscopy, 42.86%, 31.42%, 20.00%, 2.86% and 2.86% were involved in the descending colon, sigmoid colon, transverse colon, ascending colon and whole colon, respectively.The left colon was the main part, with clusters and bands Mucosa-like erythema, ecchymosis, erosion, and even ulcers.No rectum was involved in 35 patients.Conclusion:The typical manifestation of IC is sudden abdominal pain and bloody stool.Abdominal CT in emergency department has obvious suggestive value for early diagnosis of this disease.Colonoscopy is the main diagnostic method for this disease.
1999年对358批中成药品进行微生物限度检验,有47批的中成药品细菌数不符合规定.
目的:随机取抽验细菌数超限的中成药20批,对培养检出的芽孢杆菌进行鉴定.方法:根据培养检出的16株芽孢杆菌的形态、生理生化、碳源及氮源利用等32项特征鉴定到种.结果与讨论:16株芽孢杆菌中,巨大芽孢杆菌3株;枯草芽孢杆菌8株;环状芽孢杆菌3株;蜂房芽孢杆菌1株;球形芽孢杆菌1株.从中成药检出以上芽孢杆菌,说明中成药现行幅射剂量可能不足,或是保存期间再次受微生物污染,具体原因待进一步探讨.建议今后的<中国药典>,在[微生物限度]检查项目中,应当考虑增加有关芽孢杆菌的质控内容.