目的:探究3D动画结合微信公众平台在"组织学与胚胎学"教学中的效果及其应用价值分析.方法:选取广东江门中医药职业学院2022级康复治疗技术专业两个班共103名学生为研究对象,随机选取其中一个班49人作为对照组,采取传统教学法进行教学,另外一个班54人作为实验组,在传统教学法基础上采取3D动画结合微信公众平台进行教学.课程完成后,对两组学生进行考核,并对考试成绩进行统计学分析,以评价其教学效果.结果:实验组的考试成绩[(73.72±12.31)分]优于传统教学组[(65.18±12.34)分](P＜0.01),差异具有统计学意义(P＜0.05).结论:3D动画结合微信公众平台应用在"组织学与胚胎学"教学中可提高康复技术专业学生的考试成绩和教学质量,具有一定的推广价值.
Objective. Ischemia-reperfusion is an ongoing clinical challenge that can lead to a series of pathological changes including oxidative stress. The inhibition of soluble epoxide hydrolase inhibitor (sEH) by 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea (TPPU) results in an anti-inflammatory, cardioprotective, and blood vessel growth-promoting effects. Therefore, this study focused on the protective effect of TPPU on a rat pheochromocytoma (PC-12) cell oxidative stress model induced by H2O2. Methods. CCK-8 and Hoechst 33342 were used to evaluate cell apoptosis and western blot to detect the apoptotic proteins and brain-derived neurotrophic factor (BDNF) expression. Result. The incubation with 100 mu M, 50 mu M, and 25 mu M TPPU significantly increased PC-12 cell viability. Epoxyeicosatrienoic acid (EET) pretreatment also protected PC-12 cells from oxidative stress. In addition, TPPU reduced caspase-3 and Bax expression and induced Bcl-2 expression, and EETs exerted the same effect on caspase-3 expression as TPPU. A positive relationship was found between TPPU or EET incubation and BDNF expression. Conclusion. These results revealed that TPPU reduced PC-12 cell oxidative stress injury induced by H2O2 and promoted BDNF expression.
目的:探索维萨里3D解剖软件结合"雨课堂"在人体解剖学教学中的效果及其应用价值.方法:选取2019级护理专业两个班共120名学生为研究对象,随机选取其中一个班61人为实验组,采取维萨里3D解剖软件结合"雨课堂"进行教学;另一个班59人作为对照组,采取传统教学法进行教学.课程完成后,对两组学生考试成绩进行统计学分析,以评价教学效果.结果:实验组的考试成绩优于传统教学组(P<0.01),差异具有统计学意义(P<0.05).结论:维萨里3D解剖软件结合"雨课堂"在人体解剖学的教学中能提高学生考试成绩及其教学质量,具有一定推广价值.
含共轭侧链的引达省并二噻吩分别与1,3-茚满二酮和3-乙基绕丹宁构筑小分子WS1和WS2.通过核磁共振(氢谱和碳谱)和飞行时间质谱对目标小分子进行结构表征.通过测试目标小分子的吸收光谱和循环伏安曲线,研究末端的种类对小分子的光物理性质和电化学性质的影响.结果表明,末端为1,3-茚满二酮的WS1具有更加宽的吸收光谱(最大吸收峰达到567 nm);WS1和WS2具有相当的能级,说明末端的种类对小分子的能级影响不大,-5.45 eV的HOMO能级水平能够与常见的受体材料匹配.
