目的 分析深圳市两起鹦鹉热疫情的流行病学特征和影响因素,为制定防控措施提供科学依据.方法 采用现场流行病学方法收集深圳市两起鹦鹉热疫情处置相关资料,应用描述性流行病学分析方法了解病例发生情况及流行病学特征.结果 2023年深圳市宝安区、福田区相继出现两起人感染鹦鹉热衣原体疫情,共有2例病例,无死亡病例.2例病例均居家饲养鹦鹉,有发热、四肢肌肉酸痛等症状,暴露时长分别为15d和33d.共同暴露者调查分析显示,宠物店养鸟职业人群中未发生感染情况(0/13),家庭同住人员或亲朋好友非职业人群中有2例出现发热、肌肉酸痛症状,但拒绝采样.外环境中鹦鹉热衣原体阳性检出率是58.0%(29/50).结论 鹦鹉热衣原体感染为偶发感染,近距离长期无防护亲密接触是主要感染方式,暂未发现人传人.建议加强鹦鹉热环境和相关人群健康监测工作,以预防和控制鹦鹉热疫情.

目的 对深圳市1例输入性恶性疟死亡病例进行流行病学调查分析,为科学防治恶性疟提供参考依据.方法 访谈收治医生和患者家属,收集分析该病例临床和流行病学资料.结果 该病例发病前在乌干达务工,2020年1月回国,回国后第10天出现发热、发冷、发汗、头痛、腹泻、全身酸痛等症状,发病第2天前往某民营医院就诊,拟诊为"感染性发热",服药后症状未见好转.发病第3天进行血液检查,结果显示疟原虫,考虑"疟疾",予将其转院治疗.入院后,给予蒿甲醚抗疟、抗炎、降颅压、脏器功能支持等对症治疗,然而病情进一步加重.发病第6天该病例因脑型疟、多器官功能衰竭而死亡.血涂片镜检查见恶性疟原虫,PCR基因鉴定为恶性疟原虫.结论 综合流行病学史、临床症状和实验室检测结果显示,这是1例输入性恶性疟病例,诊治延误是引起该病例死亡的主要原因.

目的 查明深圳市1例疑似本地间日疟病例的感染来源,为疟疾疫情的处置提供科学依据.方法 查阅患者就诊病历,收集相关流行病学资料;采用镜检和荧光PCR方法进行虫种判定;对患者所在疫点采用全通宵诱蚊灯法和双层叠帐人饵诱捕法,进行按蚊种群和密度调查;人群外周血疟原虫RDT检测以筛查传染源,开展疫点群众健康监测,室内杀虫剂滞留喷洒灭蚊.结果 患者于2021年3月9日从海南省五指山市来深圳市大鹏新区工作,5月10日因发热2天,伴畏寒、头痛、乏力就医,初诊为"急性上呼吸道感染",予抗感染、退热药物对症治疗后无明显好转.5月11日-14日患者反复出现畏寒、发热、头痛等症状,体温高达40℃.5月15日对患者血样进行疟疾RDT筛查,结果为阳性,血涂片镜检和荧光PCR方法复核确诊为间日疟.患者发病前2个月未离开过大鹏新区,否认有境外疟疾疫区旅居史和输血史.2018年9月-2020年9月患者在云南省德宏州盈江县那邦镇服兵役,期间有中缅边境执行任务史,否认感染过疟疾.5月16 日-18日对患者工作居住地大鹏新区实践基地及曾留宿住所大围村,采用全通宵诱蚊灯法和双层叠帐人饵诱捕法开展媒介监测未发现传疟按蚊,对基地275名员工和大围村居民125名开展疟疾RDT筛查,结果为阴性.对上述人员开展1个月的健康监测,未发现疑似疟疾症状者.患者所旅居省份云南、海南所在地区均连续3年以上无本地感染疟疾病例报告,而缅甸边境为间日疟流行区.结论 根据患者临床表现、实验室检查结果,结合流行病学调查结果判断该病例为缅甸输入间日疟病例,感染源推测为经疟原虫感染阳性按蚊跨境叮咬所致.

目的 分析2016-2020年深圳市传染病类突发公共卫生事件监测结果的流行病学特征.方法 在国家突发公共卫生事件报告管理信息系统中导出2016-2020年深圳市突发公共卫生事件数据,按病种、地区和机构类型描述性分析暴发疫情的发生特点,用SPSS 22.0统计分析.结果 排除2020年报告的新冠肺炎事件,2016-2020年深圳市共报告233起传染病突发公共卫生事件相关信息,发病6 271例,死亡2例,罹患率3.87％,病死率0.03％.其中2018年罹患率最高,为5.20％.聚集性疫情事件164起,占突发公共卫生事件相关信息总数的70.39％,涉及7种传染病,病例数与发生事件起数最多的病种为水痘(100起,3 565例)和感染性腹泻(41起,1491例),分别占聚集性疫情事件总数的60.98％和25.00％.78.45％呼吸道传染病聚集性疫情事件发生在小学,58.33％肠道传染病聚集性疫情事件发生在幼儿园,两种传染病事件在幼儿园、小学、初中、高中和大专院校及其他场所的构成比存在显著性差异.结论 应采取综合防控策略,针对不同人群中发生风险较高的传染病病种,从降低人群易感性、落实及早报告与停课措施、监测流行株,以及加强培养个人卫生防护习惯等多方面制定防控策略.

目的 通过对深圳市在新型冠状病毒肺炎(COVID-19)疫情期间输入性疟疾流行情况和所实行的防控措施进行总结分析,为新冠病毒疫情下做好输入性疟疾防治工作提供参考.方法 收集2017-2021年深圳市疟疾疫情防治资料,采用描述流行病学方法分析疟疾流行情况、采取的措施及防治效果.结果 2017-2021年深圳市共报告104例疟疾确诊病例,均为境外输入性病例,97.1％由非洲输入;以恶性疟为主,占80.8％;发病年龄以青壮年为主,20～49岁年龄段占发病人数的81.7％;患者以境外务工人员居多,占59.6％.全年各月均有疟疾病例报告,8月最多13例,其次是9月12例.2017-2021年共布放诱蚊灯709台,共捕获蚊子3 523只,平均蚊密度为2.60只/灯·夜,未发现有按蚊,优势蚊种均为致倦库蚊.在新冠肺炎疫情期间,深圳市从完善多部门合作联防的工作机制、加强筛查与监测、人员培训、蚊媒控制、物资保障等几方面实施了一系列措施,做到早发现、早转运、早隔离和早治疗.结论 深圳市在防控输入性新冠肺炎的同时全面实施一系列防控输入性疟疾措施并取得了积极的成效,实现了及时识别发现病例并有效救治,阻止了疟疾重症及死亡病例发生,防止疟疾疫情传播和扩散.

目的 分析广东省首例境外输入性新型冠状病毒肺炎合并卵形疟病例的发病和诊疗过程,为新型冠状病毒肺炎疫情期间疟疾的防控策略制订提供依据.方法 对2020年12月19日深圳市国外入境集中隔离的经龙岗区健康驿站主动病例排查的新型冠状病毒肺炎合并疟疾疑似病例开展流行病学调查,采集病例的鼻咽拭子和血液样本进行检测并送上级部门复核,对患者的临床资料和流行病学调查结果进行分析.结果 该病例为境外务工人员,男,47岁,于2020年12月19日从肯尼亚回国,机场入境后经闭环管理转运至健康驿站集中隔离.12月25日新型冠状病毒核酸检测初筛阳性,12月26日经深圳市疾病预防控制中心复核确认为新型冠状病毒核酸阳性;疟原虫快速诊断试纸(RDT)检测阴性,镜检疟原虫阳性,荧光聚合酶链反应(PCR)复核确认为卵形疟.结论 根据患者流行病学史、临床表现及实验室检测结果判断为新型冠状病毒无症状感染者合并卵形疟.

OBJECTIVE:To analyse the epidemiological characteristics of family clusters of COVID-19 and the three stages of the comprehensive non-pharmaceutical interventions and measures implemented in Shenzhen.METHODS:The epidemic curve of COVID-19 was drawn and the impact of the comprehensive non-pharmaceutical interventions and measures was analysed by the different periods of the epidemic.RESULTS:A total of 427 cases (417 confirmed cases and 10 asymptomatic infectious cases) were reported in Shenzhen, of which 259 (60.7%) were clustered cases. 97 cluster events were drawn and most cluster events (97.3%) occurred in families. There were three stages of the COVID-19 epidemic in Shenzhen. The epidemic increased rapidly, but the peak lasted for a short time, while the decline in incidence was rapid and large.CONCLUSIONS:Family clusters were the main feature of the COVID-19 outbreak in Shenzhen in 2020, and the Shenzhen government rolled out a quick response to the epidemic. Non-pharmaceutical interventions and measures were proven to have effectively contained community transmission, limit the transmission to aggregation and reduce the scale of transmission within a household.

The current coronavirus disease 2019 (COVID-19) pandemic has posed an unprecedented challenge to global health (1-3) The clinical symptoms of COVID-19 are similar to those of malaria, such as fever, myalgia, fatigue, headache, and gastrointestinal symptoms Due to the heavy burden of medical services and the possible shortage of resources caused by the long-term COVID-19 pandemic, the risk of coinfection of malaria and COVID-19 is a matter of particular concern Here we reported the first case of COVID-19 coinfection with Plasmodium ovale (P ovale) malaria in a 47-year-old man who had been previously diagnosed with Plasmodium infection and incompletely treated with antimalarial drugs The 47-year-old man worked from October 30, 2018 to December 16, 2020 in Masindi, Uganda, in an area dually affected by malaria and COVID-19 On December 19, 2020, the nasopharyngeal swab for COVID-19 virus testing using reverse transcriptase polymerase chain reaction (RT-PCR) and malaria rapid diagnostic testing (RDT) both had negative results when the patient returned from Uganda and entered Shenzhen City, Guangdong Province, China However, on December 25, the nasopharyngeal swab for COVID-19 virus test result was positive, and the patient was admitted to a COVID-19 ward for further observation and symptom control on the next day On December 29, the patient experienced chills, fever, muscle pain, and other clinical symptoms On December 31, the results of blood smear test showed that the different blood stages of P ovale, including trophozoites and schizonts, were consistent with P ovale (Figure 1) In addition, the blood smear identified trophozoites of P ovale with a parasitemia of 0 01% The plasmodial ssrRNA (MW768131) and P ovale sp tryptophan-rich antigen (potra) (MW872056) gene were amplified by nested PCR, respectively (4-6) After sequencing, the protozoan was identified as P ovale wallikeri (P o wallikeri) The patient’s symptoms were mild and resolved completely after treatment with primaquine for 24 hours The result of RT-PCR detection of COVID-19 virus swab tested negative on January 1, 2021 During hospitalization, the patient did not have cough, shortness of breath, or other respiratory symptoms including decreased oxygen levels or COVID-19 infection, and did not require any oxygen supply On January 6, 2021, the blood smear test results were negative for P ovale According to his epidemiological history, clinical manifestations, and laboratory test results, this patient was preliminarily identified as an imported case of COVID-19 and P o wallikeri malaria coinfection in Uganda The patient was recently diagnosed with malaria on December 10, 2020 in Uganda, after which he left this area During treatment on December 16, there was a possibility of reinfection, which suggested that COVID-19 might induce the current relapse of P ovale Similarly, a case of COVID-19 and P vivax coinfection was reported by Kishore et al , which also highlighted the possibility of COVID-19 infection in inducing current malarial relapse (7) Associated cytokine response with systematic illness has been postulated in P vivax relapse (8) The COVID-19 infection, with its cytokine response, was assumed to induce the P ovale relapse of patient More trials are needed to illustrate the mechanism of COVID-19 in inducing malaria relapse During the COVID-19 pandemic, consistent diagnosis of malaria and other infectious diseases should still be prioritized (7,9-11), especially in the areas with endemic infectious diseases such as those in Africa In addition, invested funds related to malaria elimination were reduced or interrupted and might have lead to the interruption of malaria-related diagnostic tools and drug supply, which might have delayed targets and implementation of the malaria control strategies In conclusion, it is necessary to further study the risk factors, clinical outcomes, treatment challenges, and prognosis of cases on COVID-19 coinfection with other pathogens Given the risk of these diseases, the following comprehensive prevention and control strategies were formulated: 1) 14 days of centralized isolation medical observation for entry personnel in medium and high-risk areas should be implemented, as well as screening for pathogens such as Plasmodium;2) publicity and education on COVID-19 prevention and control of malaria and other diseases should be continued to reduce the burden of disease or death due to misdiagnosis and missed diagnoses;3) it is necessary to build human health center communities that supplement existing prevention and control strategies for endemic infectious diseases including COVID-19, malaria, etc Protecting the health and safety of the global community can only be accomplished with joint effort

深圳地区曾是疟疾高发区之一,1979年建市后,由于城市建设迅速发展,大量外来劳务工流入,流动人口持续增多,大量人群暴露在疟疾感染中,疟疾疫情在1984年和1993年出现大流行,特别是1984年疟疾的发病率达到1097.86/10万.为了有效地控制和消除疟疾,深圳市因地制宜采取了综合性的防治措施,包括及时开展"三热病人"血片镜检,应用疟疾LDH金标层析试剂快速检测疑似样本,根治现症病人,对疟疾暴露的高危人群使用溴氰菊酯浸泡的防蚊蚊帐等控制措施.此外,随着深圳城市化进程的不断完善,卫生条件不断提高,按蚊的孳生地逐渐减少,也促进了疟疾的进一步消除.2014年来在深圳市十个区的不同自然环境设置调查点,采用诱蚊灯捕蚊法开展按蚊媒介调查,均未发现传疟按蚊.2000年后,疟疾发病率呈持续下降的态势,2003年起下降到1/10万以下,疫情呈现低水平的散发状态,2010年开始深圳市已连续9年无疟疾本地病例,达到了消除疟疾目标.但是,近年来由于经济全球化、劳务输出、经商、旅游等因素,深圳市人群来往频繁,输入性疟疾病例呈现出日益增多的趋势,输入性疟疾型别多,输入地广泛,是一个重大的公共卫生问题,对巩固疟疾消除成果也是一个巨大的挑战.

目的 掌握深圳市水痘暴发疫情流行特征及水痘-带状疱疹病毒(varicella-zoster virus,VZV)病毒株的基因特征,在基因分型的基础上,探索疫情高发的原因,为水痘预防控制工作提供科学依据. 方法 对2013-2017年深圳市报告的水痘暴发疫情进行描述性流行病学分析.对部分临床诊断水痘病例采集疱疹液标本并提取DNA,采用限制性片段长度多态性聚合酶链反应(PCR-RFLP)技术鉴定毒株,并通过测序比对分析其基因型. 结果 2013-2017年深圳市共报告水痘暴发疫情579起,有两个高峰期,分别为3-6月及11月-次年1月;以龙岗区、罗湖区和南山区报告疫情起数居多,分别占31.43％、17.27％和11.40％;中小学和托幼机构是主要发生场所;疫情最长持续时间为120 d.17例患者水痘病毒核酸检测阳性,VZV均为J型毒株. 结论 2013-2017年深圳市水痘疫情形势严峻,VZV流行毒株为J型.应对水痘易感人群加强2剂次水痘疫苗接种工作,预防控制水痘疫情.

目的 了解大鹏新区居民华支睾吸虫和土源性线虫感染现状,为制定防治策略提供科学依据.方法 根据《广东省肝吸虫病和土源性线虫病监测方案》,采用分层整群抽样的方法,按地理方位选取5个自然村作为调查点.收集调查对象粪便,采用改良加藤氏厚涂片法检查寄生虫卵;3～＜10岁儿童透明胶纸肛拭法检测蛲虫卵;描述流行病学研究方法分析寄生虫感染人群分布特征.结果 大鹏新区3个街道5个调查点共调查居民1 000人,肠道蠕虫总感染率为1.50％(15/1 000),其中蛲虫感染率为1.00％(10/1 000),华支睾吸虫感染率为0.50％(5/1 000);蛔虫、鞭虫、钩虫等其他土源性寄生虫卵未检出.大鹏、葵涌、南澳3个街道居民的寄生虫感染率分别为1.75％、1.50％和1.00％,不同街道感染率差异无统计学意义(P＞0.05).不同年龄组人群感染率差异有统计学意义(P＜0.05),0～＜10岁年龄组感染率最高为3.95％,均为蛲虫感染;其次为40～＜50年龄组,华支睾吸虫感染率为1.28％;男、女性别感染率差异无统计学意义(P＞0.05).结论 大鹏新区居民肠道寄生虫感染率较低,但儿童蛲虫感染及成人华支睾吸虫感染的防治工作需要重视和加强.

The study was to understand Angiostrongylus cantonensis infection status in host animals and populations in Shenzhen. In 2016-2017, 10 different ecological environments were selected, and intermediate and definitive hosts collected at the sites were examined using the enzyme digestion and dissection method to determine their infection status. Meanwhile, serum was collected from outpatients and healthy people. The enzyme-linked immunosorbent assay test was performed to detect serum IgG-specific antibodies to A. cantonensis, and serological characteristics of the populations were analyzed. A total of 300 Achatina fulica samples had an A. cantonensis infection rate of 10.67% (32/300) and an average infection intensity of 68.7 per snail, whereas 302 Pomacea canaliculata samples had an infection rate of 6.29% (19/302) and an average infection intensity of 31.4 per snail. Although both infection rate and infection intensity were lower in P. canaliculata than in A. fulica, infection intensity was significantly different (p < 0.001). Among 238 definitive-host rodents, 22 were infected with A. cantonensis. The infection rate in Rattus norvegicus was 14.68% (16/109), significantly higher than that in Rattus flavipectus (p < 0.05). The seroprevalence of A. cantonensis in the 900 outpatients and 1500 healthy people was 7.11% (64/900) and 1.87% (28/1500), respectively. Thus, the infection rate was significantly higher in outpatients than in healthy people in Shenzhen (p < 0.001). This study revealed a wide distribution and the prevalence of A. cantonensis in host animals and populations in Shenzhen, therefore, it is necessary to strengthen the current monitoring of the disease to prevent a potential outbreak.

目的 了解深圳市输入性血吸虫病的流行病学特征,为制订防制策略提供科学依据.方法 收集2010-2014年深圳市输入性血吸虫病的疫情资料,采用描述流行病学方法进行统计分析.结果 2010-2014年全市共报告输入性血吸虫病病例324例,均为慢性血吸虫病,无急性病例报告.所有病例由国内血吸虫病疫区输入,其中湖北149例(占46.0％)、湖南91例(占26.6％)、江西31例(占9.1％)、四川22例(占6.9％)、安徽16例(占4.7％),其他省份共计15例(占4.4％).全年12个月均有血吸虫病报告,5～11月报告病例数较多,占病例总数的73.1％ (237/324).病例男女性别比为2.3∶1,集中在30～70岁组,病例构成比为77.5％ (251/324).2010-2014年75.3％(244/342)的输入性病例由市级医院诊断和报告,其余由区级及街道综合性医院报告.结论 深圳市输人性血吸虫病的防制应重点加强往返疫区流动人口血吸虫病的监测和管理,同时提高基层医疗机构临床医生对于血吸虫病的诊治能力和水平.

Objective To investigate the inhabiting behaviors and ecological distribution characteristics of Pomacea canaliculata in Shenzhen,and examine the primary environmental factors that influence the ecological distribution of Pomacea canaliculata. Methods Pomacea canaliculata was collected from 16 habitats,which were classified into 3 groups by the density. Ecological and environment factors of the 3 groups were compared including vegetation height ,vegetation width,water temperature,pH value,dissolved oxygen,ammonia nitrogen,nitrate nitrogen,Cipangopaludina cathayensis density,and the concentration calcium,copper ion and lead. Results There was statistically significant difference in dissolved oxygen, the density of Pomacea canaliculata ,vegetation height ,vegetation width ,ammonia nitrogen and the density of Cipangopaludina cathayensis(P<0.05). The density of Pomacea canaliculata was positively correlated to the vegetation height,vegetation width,dissolved oxygen and the density of Cipangopaludina cathayensis(r>0.6,P<0.05),but was negatively related to the concentration of ammonia nitrogen(r=-0.894,P<0.05). Vegetation height and ammonia nitrogen were the main factors influencing the density of Pomacea canaliculata. Conclusion The ecological distribution of Pomacea canaliculata was affected by various environmental factors such as vegetation and the physical and chemical characteristics of water.

目的 研究对比两种不同水域中,藁杆双脐螺的生长状况及其生态学特征.方法 选择代表水域,采集螺体进行形态学鉴定;同时采集水样标本,进行实验室检测,分析氨氮、硝氮,以及几种重金属含量.结果 水质较差处的螺体平均直径和壳高均大于水质较好处,且水质较差处发现两种形态的螺体;两处水样检测结果表明,水质差组中的氮含量及Mn、Fe元素均高于水质良好组,差异有统计学意义(P＜0.05).结论 藁杆双脐螺生存适应能力强,在两种不同水域均能生长,且在水质较差处生长更优.

Objective To analyze the spatial distribution and spatial-temporal characteristics of Biomphalaria straminea in Shenzhen,and provide the evidence for monitoring the risk of schistosomiasis mansoni spreading.Methods The data of Biomphalaria straminea density of rives across Shenzhen area were collected. The spatial - temporal distribution characteristics of Biomphalaria straminea were analyzed by the GIS spatial autocorrelation and local spatial aggregation. Results The distribution areas of Biomphalaria straminea in Shenzhen are highly clustered. There is a significant global autocorrelation. The density distribution is similar of the snails in the adjacent area. The local spatial aggregation analysis of the survey point was applied. It was found that the rivers which were intense aggregations of the snail 'distribution are mainly distributed in the coastal area ,while the density aggregation is not different far from the coast. The snail density is inconsistent in the same river. It reflects the influence of the difference of the internal environment of the river on the difference of the snails 'distribution. The quality of the water is an important factor affecting the distribution of Biomphalaria straminea. The distribution is closely related to the local geographical elements and the seasons of the various regions. Conclusion The Biomphalaria straminea distribution in Shenzhen has global and local spatial autocorrelations. There was an intense aggregation of the snails'distribution,which is obviously associated with the environmental factors.

Objective Biomphalaria straminea is an important intermediate host of Schistosoma mansoni, and the distribution and diffusion of it are greatly affected by environmental factors.This study explores the characteristics of spatial distribution of B.straminea and influencing factors, so as to provide the evidence for forecasting the distribution of B.straminea breeding and monitoring the risk of schistosomiasis mansoni spreading.Methods The data of B.straminea density of rivers across Shenzhen administrative area were collected.The characteristics of spatial distribution and the correlation with environmental factors were analyzed by the spatial autocorrelation and statistics.Results There was an intense aggregation of the snails' distribution, and its density levels were affected by environmental factors.There were no snails when the water quality was excellent or poor.The snails were mainly distributed in areas that the slope was from 0 to 9 and the vegetation index was between 3 and 9 (poor-good).The regional differences of temperature and humidity had little effect on the snails' distribution.Finally, the influence of environmental factors on snail density was different, that was slope＞vegetation index＞ humidity＞water quality＞temperature.Conclusion The distribution of B.straminea is obviously associated with the environmental factors, which have the impact on the living condition, density and distribution of B.straminea.

Objective To analyze and evaluatethe methods and strategy for control the malaria epidemic by controlling the migration of floating population in Shenzhen. Methods The data of malaria cases, control methods and strategies of Shenzhen between 1980 and 2016 were collected from the Disease Reporting Information System of Chinese Center for Disease Control and Prevention. Results A total of 41851 malaria cases were reported in Shenzhen city from 1980 to 2016, with an annual mean incidence of 25.38 per 100 thousand and an annual mean case of 1131. The highest annual incidence wasreached 1833.37 per 100 thousand in 1984. The least annual incidence of 0.24 per 100 thousand was reported in 2006. The regional distribution of malaria cases were mainly in Longgang district and Baoan district in Shenzhen, anda total of 26782 cases were reported, accounting for 63.99%of the total number of cases(26782/41851). There were cases reported every month in the whole year. The ratio of male to female cases was 13.06:1. The age distribution concentrated mainly in 20~45 years old. The top three of proportion of malaria cases were construction workers, brick-making and quarry workers. Conclusion The epidemic of malaria outbreaks causing by migrant floating population had been effectively controlled by strengthening the migrant floating population management and active prevention and treatment of malaria. The results of the study indicated that the methods and strategies adopted by Shenzhen city for controlling malaria were scientific, feasible and effective.

目的 了解深圳市消除疟疾主要措施的执行情况,评估实施效果.方法 收集2012-2015年深圳市疟疾疫情监测、病例处置、业务培训等消除疟疾工作资料,根据广东省消除疟疾实施方案工作指标的完成情况分析实施效果.结果 2012-2015年深圳市共血检“三热”病人98 090人次,年平均血检率为2.3‰,检出境外输入性疟疾126例,其中恶性疟93例(73.81％),间日疟28例(22.22％),卵形疟4例(3.17％),三日疟1例(0.79％).疟疾病例实验室确诊率及规范治疗率均为100％.疟疾疫情上报、个案调查及疫点处置均按“1-3-7定点清除”工作模式开展.近3年从事疟防、临床及实验室工作的相关人员接受消除疟疾专业培训的比例达到95％.卫生部门通过与出入境检验检疫机构建立疟疾联防机制以及对涉外企业归国人员排查,及时发现和处置输入性病例24例.结论 深圳市2012-2015年无本地疟疾感染病例和输入继发病例报告,消除疟疾主要措施执行良好,效果显著.但仍要加强对外出非洲和东南亚高疟区务工返回人员疟疾监测和管理,保证2017年消除疟疾目标的实现.

目的 了解深圳市居民重点食源性寄生虫感染现状及影响因素,为制定防治策略提供依据.方法 采用随机分层抽样的方法,对全市各区的抽样点的居民进行华支睾吸虫、广州管圆线虫血清学检查和流行病学调查,华支睾吸虫血清学阳性者加做病原学检查.结果 共检测血清1 671份,总感染率为14.18％;男性感染率为17.00％,女性为10.94 ％;31～40岁人群感染率最高为19.71％,20岁以下年龄组最低为7.89％;个体私营人群感染率最高为20.25％,学生及儿童感染率最低为8.28％;初中文化程度人群感染率最高为18.17％,大专及以上文化程度最低为10.08％;不同性别、不同年龄组、不同职业和文化程度人群感染率差异均有统计学意义(P＜0.05).危险因素Logistic分析表明:男性、文化程度较低、吃鱼生是食源性寄生虫感染的危险因素,而生熟砧板分开、饭前便后洗手及知晓寄生虫病健康危害为食源性寄生虫感染的保护性因素.结论 深圳市居民食源性寄生虫感染有上升趋势,文化程度和饮食习惯是重要原因,要发挥现代传媒手段,大力倡导健康饮食行为.