Two recently published studies have provided new insights into the long-term effects of COVID-19 on the nervous system.

Nature Reviews Neurology is interviewing individuals who are driving efforts to address disparities in neurology through a broad spectrum of diversity, equity and inclusion initiatives. We spoke with Victor Rivera from Baylor College of Medicine about his work to address disparities in multiple sclerosis care in Latin American and other populations.

The oral orexin receptor 2-selective agonist oveporexton ameliorates the symptoms of narcolepsy type 1, according to a phase II trial.

New research indicates that in a mouse model of Parkinson disease, α-synuclein is trafficked from the brain to the gut by CD11c-expressing macrophages.

In a plenary lecture at the XXVI World Congress of Neurology, Anthony Lang presented a new biological classification model for Parkinson disease.

Two new studies have provided important mechanistic insights into TDP-43 pathology, a hallmark of neurodegenerative conditions such as amyotrophic lateral sclerosis and frontotemporal lobar degeneration.

n α-synuclein seed amplification assay can reliably identify people with Parkinson disease, even at the prodromal stage, new research indicates.

Loss of myelin integrity, which occurs during ageing, promotes deposition of amyloid-β in the brain, according to new research.

A genetic variant of the WNT receptor LRP6 exacerbates synapse degeneration in mouse models of ageing and Alzheimer’s disease, according to new research.

A recent paper published in Nature reports on an ambitious project to construct standardized charts to aid recognition of typical and atypical development of the human brain.