Introduction: Doppler ultrasonography (DUSG) enables intraoperative assessment of renal perfusion during partial nephrectomy. This study evaluated the feasibility of DUSG and compared its outcomes with indocyanine green (ICG) fluorescence imaging and a control group (CG) without intraoperative perfusion imaging. Methods: We retrospectively analyzed 426 patients undergoing minimally invasive partial nephrectomy between 2018 and July 2025. Ischemia verification was performed using DUSG in 174 patients (41%) and ICG in 29 patients (7%). The CG included 223 patients (52%). Selection of imaging modality depended on the surgeon’s preference and intraoperative findings. Perioperative, oncological, and functional outcomes were analyzed using one-way analysis of variance and chi-square tests. Results: No significant differences were observed in tumor size, BMI, warm ischemia time, blood loss, RENAL score, or complication severity assessed by the Clavien-Dindo classification. Selective clamping and clamp adjustment were significantly more frequent in the DUSG and ICG groups compared with controls (both p < 0.001). Positive surgical margin rates were low and comparable between groups. Conclusion: Both DUSG and ICG represent safe and effective methods for ischemia verification; however, DUSG offers the advantages of lower cost, wider availability, and no risk of contrast-related adverse reactions, making it a practical option for routine clinical use.

INTRODUCTION:Uveal melanoma is the most common primary malignant intraocular tumor in adults. A major prognostic factor is the cytogenetic profile of the tumor, particularly the presence of monosomy of chromosome 3, which is associated with an increased risk of developing distant metastases. The aim of this study was to determine whether there is a relationship between the metabolic activity of the tumor assessed by SUVmax (maximum standardized uptake value) in PET/CT or PET/MRI and the presence of monosomy 3 in the tumor cytogenetic profile. MATERIAL AND METHODS:A total of 37 patients with uveal melanoma were included in this retrospective analysis. All patients underwent staging wholebody PET/CT or PET/MRI with calculation of SUVmax, followed by enucleation of the affected eye and cytogenetic examination of the tumor. All patients were examined and subsequently treated between 2009 and 2024 at the Department of Ophthalmology, University Hospital Plzeň. RESULTS:Monosomy 3 was detected in 21 patients. In this group, SUVmax values ranged from 2.7 to 14.5 (mean 6.6; median 6.5). Metastatic dissemination occurred within 5 years of diagnosis in 16 patients (76.2%), and in an additional four patients after a longer interval. Disomy 3 was present in 16 patients, with SUVmax values ranging from 1.1 to 8.0 (mean 3.4; median 3.4). Metastatic spread occurred in only one patient (6.3%). The difference in SUVmax values between the groups was highly statistically significant (p = 0.00012). CONCLUSION:Higher SUVmax values were associated with the presence of monosomy 3 and an increased risk of metastatic progression. PET/CT and PET/ MRI imaging may be beneficial not only for diagnosis and primary staging of metastatic disease, but also for indirect estimation of the tumor's genetic variant.

We aimed to find predictive tumour characteristics as detected by interim positron-emission tomography/magnetic resonance imaging (PET/MRI) in cervical cancer patients. We also investigated the type of interim response. Furthermore, we compared the investigated parameters with disease-free (DFS) and overall survival (OS) outcomes. We evaluated 108 patients treated between August 2015 and January 2023 with external-beam radiotherapy (EBRT) and image-guided adaptive brachytherapy (IGABT) who had undergone pretreatment staging, subsequent mid-treatment evaluation after completed EBRT and definitive restaging 3 months after completing the whole treatment using PET/MRI. Patients were then divided into two groups based on the RECIST and PERCIST criteria: responders (achieving complete metabolic response, CMR) and non-responders (non-CMR). These two groups were compared using selected parameters obtained at pre-PET/MRI and mid-PET/MRI. The early response to treatment as evaluated by mid-PET/MRI was categorized into three types: interim complete metabolic response, interim nodal response and interim nodal persistence. Mid-TLG‑S (the sum of total lesion glycolysis for the primary tumour plus pelvic and para-aortic lymph nodes) parameter showed the best discriminatory ability for predicting non-CMR. The second factor with significant discriminatory ability was mid-MTV‑S (the sum of the metabolic tumour volume of the primary tumour plus pelvic and para-aortic lymph nodes). The strongest factor, mid-TLG‑S, showed a sensitivity of 40

Photon-counting detectors are a promising new technology for computed tomography (CT) systems. They provide energy-resolved CT data at very high spatial resolution without electronic noise and with improved tissue contrasts. This review article gives an overview of the principles of photon-counting detector CT, of potential clinical benefits and limitations, and of the experience gained so far in pre-clinical installations.

The aim of this article is to acquaint the gynaecological public with our experience with the use of computed tomography in the diagnosis of fluid collections in women with clinical suspicion of complicated pelvic inflammation or a complication after gynaecological surgery. We present diagnostic dilemmas that radiologists deal with, including differential diagnoses. We also deal with the benefits for the referring gynaecologist, and we also discuss the possible discrepancy between his expectations and the result of the examination.